Literature DB >> 6204220

Possible involvement of folate cycle in the pathogenesis of amyotrophic lateral sclerosis.

Y Yoshino.   

Abstract

The folate cycle, which has a close correlation with nucleic acid synthesis as well as with sulfur amino acid metabolism, may have some bearing on the pathogenesis of amyotrophic lateral sclerosis. The folate cycle hypothesis offers a unified explanation of the reduction of RNA and the elevation of taurine in nervous tissue of this disease.

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Year:  1984        PMID： 6204220     DOI： 10.1007/bf00963985

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  12 in total

1.  [Free amino acids in the spinal cord of a patient with amyotrophic lateral sclerosis].

Authors:  Y Yoshino; H Koike; K Akai
Journal:  Rinsho Shinkeigaku       Date:  1976-09

2.  Aminoaciduria in pernicious anaemia and subacute combined degeneration of the cord.

Authors:  J A WEAVER; D W NEILL
Journal:  Lancet       Date:  1954-06-12       Impact factor: 79.321

3.  The effect of folate deficiency on neuronal RNA content. A quantitative cytochemical study.

Authors:  M Haltia
Journal:  Br J Exp Pathol       Date:  1970-04

4.  Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions.

Authors:  Y Yoshino; K A Elliott
Journal:  Can J Biochem       Date:  1970-03

5.  RNA content and volume of motor neurons in amyotrophic lateral sclerosis. II. The lumbar intumescence and nucleus dorsalis.

Authors:  T J Davidson; H A Hartmann
Journal:  J Neuropathol Exp Neurol       Date:  1981-03       Impact factor: 3.685

6.  RNA synthesis in normal and Newcastle disease virus infected mice.

Authors:  J S Burks; R S Murray; J Naylor; L D Jankovsky; S C Bondy
Journal:  J Neurochem       Date:  1979-02       Impact factor: 5.372

7.  [Activities of folate-derivative converting enzymes in the brain of patients with amyotrophic lateral sclerosis].

Authors:  Y Yoshino; Y Wakabayashi
Journal:  Rinsho Shinkeigaku       Date:  1983-07

8.  Free amino acids in motor cortex of amyotrophic lateral sclerosis.

Authors:  Y Yoshino; H Koike; K Akai
Journal:  Experientia       Date:  1979-02-15

9.  [Folate derivatives in motor cortex of amyotrophic lateral sclerosis (author's transl)].

Authors:  Y Yoshino; Y Wakabayashi; H Koike
Journal:  Rinsho Shinkeigaku       Date:  1981-02

10.  A new hypothesis of the etiology of amyotrophic lateral sclerosis. The DNA hypothesis.

Authors:  W G Bradley; F Krasin
Journal:  Arch Neurol       Date:  1982-11
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