Literature DB >> 6203870

Effects of prostaglandin synthesis inhibitors on tumor growth and vascularization. Experimental studies in the rat.

H I Peterson.   

Abstract

The growth rate (studied by mean tumor dry weight) and vascularization (studied by microangiography) of two transplantable rat tumors, a 20-methylcholanthrene-induced fibrosarcoma and a hepatoma, were significantly reduced by three prostaglandin synthesis inhibitors, indomethacin, diclofenac-sodium and aspirin, irrespective of whether the drugs were administered early or late during tumor growth.

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Year:  1983        PMID： 6203870

Source DB:  PubMed          Journal:  Invasion Metastasis        ISSN： 0251-1789


  11 in total

Review 1.  Tumour angiogenesis.

Authors:  F Arnold
Journal:  Ann R Coll Surg Engl       Date:  1985-09       Impact factor: 1.891

Review 2.  Accelerated genetic destabilization and dormancy: two distinct causes of resistance in metastatic cells; clinical magnitude, therapeutic approaches.

Authors:  L Israel
Journal:  Clin Exp Metastasis       Date:  1990 Jan-Feb       Impact factor: 5.150

3.  Effect of indomethacin on capillary growth and microvasculature in chronically stimulated rat skeletal muscles.

Authors:  S C Pearce; O Hudlická; M D Brown
Journal:  J Physiol       Date:  2000-07-15       Impact factor: 5.182

4.  Expression of cyclooxygenase 1 and 2 by human gastric endothelial cells.

Authors:  M A Hull; J L Thomson; C J Hawkey
Journal:  Gut       Date:  1999-10       Impact factor: 23.059

Review 5.  Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis.

Authors:  O C Trifan; T Hla
Journal:  J Cell Mol Med       Date:  2003 Jul-Sep       Impact factor: 5.310

6.  Influence of zymosan (a non-specific macrophage stimulator) and of indomethacin on liver tumours--an experimental study in rats.

Authors:  S B Holmberg; P L Naredi; G O Lindnér; I H Karlberg; P L Daneryd; L M Karlsson; A Pettersson; U Stenram; L R Hafström
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

7.  Inhibition by indomethacin of spontaneous mammary tumorigenesis in SHN mice.

Authors:  H Nagasawa; T Naito
Journal:  Breast Cancer Res Treat       Date:  1986       Impact factor: 4.872

Review 8.  Inhibition of angiogenesis by NSAIDs: molecular mechanisms and clinical implications.

Authors:  Andrzej S Tarnawski; Michael K Jones
Journal:  J Mol Med (Berl)       Date:  2003-09-06       Impact factor: 4.599

Review 9.  COX-2 inhibitors for the prevention of breast cancer.

Authors:  Louise R Howe; Andrew J Dannenberg
Journal:  J Mammary Gland Biol Neoplasia       Date:  2003-01       Impact factor: 2.673

Review 10.  Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy?

Authors:  R E Langley; S Burdett; J F Tierney; F Cafferty; M K B Parmar; G Venning
Journal:  Br J Cancer       Date:  2011-08-16       Impact factor: 7.640
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