Literature DB >> 6203372

Histamine release from the cultured mouse mast cell line PT18 in response to immunologic and non-immunologic stimuli.

K E Barrett, D H Pluznik, D D Metcalfe.   

Abstract

Cultured mouse mast cells that are dependent on spleen-derived factors for their proliferation and maintenance have been shown rapidly to release histamine in response to immunologic stimuli, concanavalin A, and ionophores A23187 and Br-x537A. These cells did not, however, release histamine when treated with compound 48/80 or adenosine 5'-triphosphate. Immunologically mediated histamine release was inhibited by theophylline and quercetin, but not by disodium cromoglycate. The results presented here are discussed in terms of the possible relationship of this cell line to mucosal mast cells.

Entities:  

Mesh:

Substances:

Year:  1984        PMID: 6203372     DOI: 10.1007/bf01973856

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  20 in total

1.  Isolation and some properties of mast cells from the mesentery of the rat and guinea pig.

Authors:  F L Pearce; M Ennis
Journal:  Agents Actions       Date:  1980-04

2.  Mast cells isolated from guinea-pig lung: characterization and studies on histamine secretion.

Authors:  K E Barrett; M Ennis; F L Pearce
Journal:  Agents Actions       Date:  1983-04

3.  A comparative study of histamine secretion from rat peritoneal and pleural mast cells.

Authors:  K E Barrett; F L Pearce
Journal:  Agents Actions       Date:  1982-04

4.  In in vitro production and cloning of the P cell, a bone marrow-derived null cell that expresses H-2 and Ia-antigens, has mast cell-like granules, and is regulated by a factor released by activated T cells.

Authors:  J W Schrader
Journal:  J Immunol       Date:  1981-02       Impact factor: 5.422

5.  Does heparin occur in mucosal mast cells of the rat small intestine?

Authors:  J Tas; R G Berndsen
Journal:  J Histochem Cytochem       Date:  1977-09       Impact factor: 2.479

6.  Ultrastructural, biochemical, and functional characteristics of histamine-containing cells cloned from mouse bone marrow: tentative identification as mucosal mast cells.

Authors:  B Sredni; M M Friedman; C E Bland; D D Metcalfe
Journal:  J Immunol       Date:  1983-08       Impact factor: 5.422

7.  T cell hybridoma-derived regulatory factors. I. Production of T cell growth factor following stimulation by concanavalin A.

Authors:  J W Schrader; I Clark-Lewis
Journal:  J Immunol       Date:  1981-03       Impact factor: 5.422

8.  Histamine release from human pulmonary mast cells.

Authors:  M Ennis
Journal:  Agents Actions       Date:  1982-04

9.  The effect of alkaline earth cations on the release of histamine from rat peritoneal mast cells treated with compound 48/80 and peptide 401.

Authors:  G Atkinson; M Ennis; F L Pearce
Journal:  Br J Pharmacol       Date:  1979-03       Impact factor: 8.739

10.  Quercetin: a novel inhibitor of Ca2+ influx and exocytosis in rat peritoneal mast cells.

Authors:  C M Fewtrell; B D Gomperts
Journal:  Biochim Biophys Acta       Date:  1977-08-15
View more
  4 in total

1.  Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma.

Authors:  Mang Yu; Michael R Eckart; Alexander A Morgan; Kaori Mukai; Atul J Butte; Mindy Tsai; Stephen J Galli
Journal:  J Clin Invest       Date:  2011-08       Impact factor: 14.808

2.  Histamine secretion induced by N-acetyl cysteine.

Authors:  K E Barrett; J R Minor; D D Metcalfe
Journal:  Agents Actions       Date:  1985-04

Review 3.  The mucosal mast cell and its role in gastrointestinal allergic diseases.

Authors:  K E Barrett; D D Metcalfe
Journal:  Clin Rev Allergy       Date:  1984-02

Review 4.  Mast cell heterogeneity: evidence and implications.

Authors:  K E Barrett; D D Metcalfe
Journal:  J Clin Immunol       Date:  1984-07       Impact factor: 8.317

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.