Literature DB >> 6202552

Identity of dihydrodiol dehydrogenase and 3 alpha-hydroxysteroid dehydrogenase in rat but not in rabbit liver cytosol.

W Wörner, F Oesch.   

Abstract

Dihydrodiol dehydrogenase and 3 alpha-hydroxysteroid dehydrogenase activity in rat and rabbit liver cytosol have been analyzed by isoelectric focussing and subsequent activity staining. Identity of the two enzymes in rat liver cytosol is demonstrated. At least 4 main enzyme forms possessing dihydrodiol dehydrogenase activity can be detected in rabbit liver cytosol. However, in this species, only one of these forms has measurable activity towards 3 alpha-hydroxysteroids.

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Year:  1984        PMID： 6202552     DOI： 10.1016/0014-5793(84)81325-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

1.  Electrophoretic and immunochemical characterization of 3 alpha-hydroxysteroid/dihydrodiol dehydrogenases of rat tissues.

Authors:  T E Smithgall; T M Penning
Journal:  Biochem J       Date:  1988-09-15       Impact factor: 3.857

2.  Structural and functional comparison of two human liver dihydrodiol dehydrogenases associated with 3 alpha-hydroxysteroid dehydrogenase activity.

Authors:  Y Deyashiki; H Taniguchi; T Amano; T Nakayama; A Hara; H Sawada
Journal:  Biochem J       Date:  1992-03-15       Impact factor: 3.857

3.  Distribution and characterization of dihydrodiol dehydrogenases in mammalian ocular tissues.

Authors:  A Hara; T Nakayama; T Harada; T Kanazu; M Shinoda; Y Deyashiki; H Sawada
Journal:  Biochem J       Date:  1991-04-01       Impact factor: 3.857

4.  Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenases.

Authors:  E Arimitsu; S Aoki; S Ishikura; K Nakanishi; K Matsuura; A Hara
Journal:  Biochem J       Date:  1999-09-15       Impact factor: 3.857

5.  Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA.

Authors:  H Shiraishi; S Ishikura; K Matsuura; Y Deyashiki; M Ninomiya; S Sakai; A Hara
Journal:  Biochem J       Date:  1998-09-01       Impact factor: 3.857

6.  Roles of the C-terminal domains of human dihydrodiol dehydrogenase isoforms in the binding of substrates and modulators: probing with chimaeric enzymes.

Authors:  K Matsuura; A Hara; Y Deyashiki; H Iwasa; T Kume; S Ishikura; H Shiraishi; Y Katagiri
Journal:  Biochem J       Date:  1998-12-01       Impact factor: 3.857

7.  Molecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder.

Authors:  Y Deyashiki; A Ogasawara; T Nakayama; M Nakanishi; Y Miyabe; K Sato; A Hara
Journal:  Biochem J       Date:  1994-04-15       Impact factor: 3.857

8.  3 alpha-hydroxysteroid dehydrogenase activity of the Y' bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significance.

Authors:  A Stolz; H Takikawa; Y Sugiyama; J Kuhlenkamp; N Kaplowitz
Journal:  J Clin Invest       Date:  1987-02       Impact factor: 14.808

9.  Isolation from pig lens of two proteins with dihydrodiol dehydrogenase and aldehyde reductase activities.

Authors:  A Hara; T Harada; M Nakagawa; K Matsuura; T Nakayama; H Sawada
Journal:  Biochem J       Date:  1989-12-01       Impact factor: 3.857
  9 in total

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