Literature DB >> 6202547

The kinetics of estrogen binding to rat alpha-fetoprotein.

B A Keel, T O Abney.   

Abstract

Fluid obtained from rat fetuses was utilized to characterize the affinity, number of binding sites, and the association and dissociation rate kinetics of the binding of estradiol and estrone to AFP. Statistical analysis demonstrated no differences when the values for the AFP-estradiol interaction were compared with those obtained for the ATP-estrone interaction. These data demonstrate that rat AFP specifically binds estradiol and estrone with a high capacity, high affinity, and similar binding kinetics.

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Year:  1984        PMID： 6202547     DOI： 10.1007/bf01952408

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Characterization of the interaction between 17 beta-estradiol and its cytoplasmic receptor in the rat anterior pituitary gland.

Authors:  K S Korach; T G Muldoon
Journal:  Biochemistry       Date:  1974-04-23       Impact factor: 3.162

2.  Mathematics of hormone-receptor interaction. I. Basic principles.

Authors:  D Rodbard
Journal:  Adv Exp Med Biol       Date:  1973       Impact factor: 2.622

3.  Comparative study on the binding of estrogens by human and rat serum proteins in development.

Authors:  E Nunez; G Vallette; C Benassayag; M F Jayle
Journal:  Biochem Biophys Res Commun       Date:  1974-03-15       Impact factor: 3.575

4.  Estrogen-binding properties of rat, mouse and man fetospecific serum proteins. Demonstration by immuno-autoradiographic methods.

Authors:  J Uriel; B de Nechaud; M Dupiers
Journal:  Biochem Biophys Res Commun       Date:  1972-02-16       Impact factor: 3.575

5.  Unique estrogen-binding properties of rat pregnancy plasma.

Authors:  M S Soloff; J E Creange; G O Potts
Journal:  Endocrinology       Date:  1971-02       Impact factor: 4.736

6.  An immunological comparison between mouse alpha-fetoprotein and the uterine estrogen receptor.

Authors:  D O Toft; T B Tomasi
Journal:  Proc Soc Exp Biol Med       Date:  1978-04

7.  Characterization of estrogen binding in the developing rat testis. Ontogeny of the testicular cytoplasmic estrogen receptor.

Authors:  T O Abney; M H Melner
Journal:  Steroids       Date:  1979-10       Impact factor: 2.668

8.  Isolation of two forms of rat alpha-fetoprotein and comparison of their binding parameters with estradiol-17beta.

Authors:  C Benassayag; G Vallette; N Cittanova; E Nunez; M F Jayle
Journal:  Biochim Biophys Acta       Date:  1975-12-15

9.  A cytoplasmic estradiol receptor in rat testicular tissue.

Authors:  T O Abney
Journal:  Endocrinology       Date:  1976-08       Impact factor: 4.736

10.  alpha-Fetoprotein is not a component of the estradiol receptor of the rat uterus.

Authors:  C Radanyi; C Mercier-Bodard; C Secco-Millet; E E Baulieu; H Richard-Foy
Journal:  Proc Natl Acad Sci U S A       Date:  1977-06       Impact factor: 11.205
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  1 in total

1.  Elucidating Binding Sites and Affinities of ERα Agonists and Antagonists to Human Alpha-Fetoprotein by In Silico Modeling and Point Mutagenesis.

Authors:  Nurbubu T Moldogazieva; Daria S Ostroverkhova; Nikolai N Kuzmich; Vladimir V Kadochnikov; Alexander A Terentiev; Yuri B Porozov
Journal:  Int J Mol Sci       Date:  2020-01-30       Impact factor: 5.923
  1 in total

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