Literature DB >> 6202075

[Postmortem DNA and RNA synthesis. Preliminary studies in human cadavers].

M Oehmichen, K Zilles.   

Abstract

Postmortem DNA and RNA synthesis was detected in tissue specimens harvested from two cadavers at different intervals between 2.5 and 32 h postmortem. Each tissue specimen was incubated for 1 h in a 3H-thymidine or 3H-cytidine solution. DNA- as well as RNA-synthesizing cells were found in skin tissue and bone marrow throughout the interval investigated. Cytidine incorporation decreased progressively during the course of the postmortem interval. DNA and RNA synthesis was also observed in cells of the testis, which were predominantly spermatogonia cells in the case of DNA. Low-grade RNA synthesis was detected in bowel epithelial cells up to 2.5 h postmortem; DNA synthesis was not present during the interval investigated. No supravital phenomena were observable in the splenic tissues examined.

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Year:  1984        PMID: 6202075     DOI: 10.1007/bf02332322

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  3 in total

1.  [Radiochemical studies on the metabolism of cadaver-skin in the supravital phase].

Authors:  S Berg; G Bode; L Sekardi
Journal:  Beitr Gerichtl Med       Date:  1974

Review 2.  [Vital reactions (opening review)].

Authors:  J Lindner
Journal:  Dtsch Z Gesamte Gerichtl Med       Date:  1967

3.  [Histoautoradiographic examinations of postmortem proliferation of the epidermis in rats].

Authors:  B Schellmann; H Schell
Journal:  Beitr Gerichtl Med       Date:  1980
  3 in total
  6 in total

1.  Time-dependent RNA synthesis in different skin layers after wounding. Experimental investigations in vital and postmortem biopsies.

Authors:  M Oehmichen; T Lagodka
Journal:  Int J Legal Med       Date:  1991       Impact factor: 2.686

2.  RNA/DNA co-analysis from bloodstains on aged polyvinyl-alcohol gloves prepared for securing evidence from the hands of victims of fatal gunshot injuries.

Authors:  Melanie Grabmüller; Cornelius Courts; Burkhard Madea; Tim Eichhorst; Christian Schyma
Journal:  Int J Legal Med       Date:  2017-09-27       Impact factor: 2.686

3.  RNA/DNA co-analysis on aged bloodstains from adhesive tapes used for gunshot residue collection from hands.

Authors:  Melanie Grabmüller; Christian Schyma; Burkhard Madea; Tim Eichhorst; Cornelius Courts
Journal:  Forensic Sci Med Pathol       Date:  2017-04-25       Impact factor: 2.007

4.  Kinetics of epidermal cells in skin from human cadavers.

Authors:  M Oehmichen; J Frasunek; K Zilles
Journal:  Naturwissenschaften       Date:  1988-06

5.  Cytokinetics of epidermic cells in skin from human cadavers. I. Dependency on the postmortal interval.

Authors:  M Oehmichen; J Frasunek; K Zilles
Journal:  Z Rechtsmed       Date:  1988

6.  Temporal course of intravital and postmortem proliferation of epidermal cells after mechanical injury. An immunohistochemical study using bromodeoxyuridine in rats.

Authors:  M Oehmichen; A Cröpelin
Journal:  Int J Legal Med       Date:  1995       Impact factor: 2.686

  6 in total

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