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Literature DB >> 6201186

Study of the target cell of the dengue virus-induced suppressor signal.

Abstract

Dengue type 2 virus (DV) induces two generations of T suppressor cells (Ts1 and Ts2) in murine spleen. The Ts2 cells produce a soluble factor ( SF2 ) which suppresses DV-specific IgM antibody plaque-forming cells (PFC). In this study the target cell of SF2 was examined. The results show that SF2 requires a third generation of T cells (T3) in order to mediate suppression. The surface phenotype of this T3 cell is Ly 1+ and the suppression mediated is antigen specific.

Entities: Gene Species

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Year: 1984 PMID： 6201186 PMCID： PMC2040952

Source DB: PubMed Journal: Br J Exp Pathol ISSN： 0007-1021

15 in total

1. Regulation of the immune response. I. Suppression of delayed-type hypersensitivity by T cells from mice expressing humoral immunity.

Authors: I A Ramshaw; P A Bretscher; C R Parish
Journal: Eur J Immunol Date: 1976-10 Impact factor: 5.532

2. Dengue virus-induced thymus-derived suppressor cells in the spleen of mice.

Authors: P Tandon; U C Chaturvedi; A Mathur
Journal: Immunology Date: 1979-12 Impact factor: 7.397

3. Host defence mechanisms against dengue virus infection of mice.

Authors: U C Chaturvedi; P Tandon; A Mathur; A Kumar
Journal: J Gen Virol Date: 1978-05 Impact factor: 3.891

4. Regulation of cellular and humoral immune responses by T-cell subclasses.

Authors: H Cantor; E A Boyse
Journal: Cold Spring Harb Symp Quant Biol Date: 1977

Review 5. Immunological circuits: cellular composition.

Authors: H Cantor; R K Gershon
Journal: Fed Proc Date: 1979-06

6. Regulation of delayed-type hypersensitivity. I. T suppressor cells for delayed-type hypersensitivity to sheep erythrocytes in mice.

Authors: F Y Liew
Journal: Eur J Immunol Date: 1977-10 Impact factor: 5.532

7. Delayed-type hypersensitivity responses to H-Y: characterization and mapping of Ir genes.

Authors: F Y Liew; E Simpson
Journal: Immunogenetics Date: 1980 Impact factor: 2.846

8. Characterization of the cytotoxic factor produced in the spleen of dengue virus-infected mice.

Authors: U C Chaturvedi; H Dalakoti; A Mathur
Journal: Immunology Date: 1980-10 Impact factor: 7.397

9. Antigen- and receptor-driven regulatory mechanisms. VIII. Suppression of idiotype-negative, p-azobenzenearsonate-specific T cells results from the interaction of an anti-idiotypic second-order T suppressor cell with a cross-reactive-idiotype-positive, p-azobenzenearsonate-primed T cell target.

Authors: M S Sy; A Nisonoff; R N Germain; B Benacerraf; M I Greene
Journal: J Exp Med Date: 1981-06-01 Impact factor: 14.307

10. Delayed-type hypersensitivity to influenza virus. Induction of antigen-specific suppressor T cells for delayed-type hypersensitivity to hemagglutinin during influenza virus infection in mice.

Authors: F Y Liew; S M Russell
Journal: J Exp Med Date: 1980-04-01 Impact factor: 14.307

8 in total

1. Dengue virus-induced helper cytokine has two polypeptide chains which bear different determinants.

Authors: P Chaturvedi; R Mukherjee; U C Chaturvedi; A Mathur
Journal: Int J Exp Pathol Date: 1991-12 Impact factor: 1.925

2. Production of dengue virus-induced macrophage cytotoxin in vivo.

Authors: L Gulati; U C Chaturvedi; A Mathur
Journal: Br J Exp Pathol Date: 1986-04

3. Identification and purification of a receptor on macrophages for the dengue virus-induced suppressor cytokine.

Authors: R Mukherjee; P Chaturvedi; U C Chaturvedi
Journal: Clin Exp Immunol Date: 1993-02 Impact factor: 4.330

4. Binding of the two polypeptide chains of dengue virus-induced suppressor cytokine to its receptor isolated from macrophages.

Authors: R Mukherjee; P Chaturvedi; U C Chaturvedi
Journal: Int J Exp Pathol Date: 1993-06 Impact factor: 1.925

Review 8. Dengue in India.

Authors: Nivedita Gupta; Sakshi Srivastava; Amita Jain; Umesh C Chaturvedi
Journal: Indian J Med Res Date: 2012-09 Impact factor: 2.375