Literature DB >> 6200112

Biochemical correlates of phenotypic reversion in interferon-treated mouse cells transformed by a human oncogene.

D Samid, E H Chang, R M Friedman.   

Abstract

Mouse interferon (IFN) induced a phenotypic reversion in RS 485, a clonal line of NIH 3T3 oncogenically transformed by a human c-Ha-rasl gene activated by Ha-MuSV long terminal repeats (LTRs). Transfected c-Ha-ras DNA, unchanged in quantity and distribution, as compared to the parental RS 485 transformed cells, was still present in these revertants; however, there was a significant reduction in the amount of c-Ha-ras specific mRNA and of c-Ha-ras specified p21 protein.

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Year:  1984        PMID： 6200112     DOI： 10.1016/0006-291x(84)91612-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  22 in total

1.  Interferon-induced revertants of ras-transformed cells: resistance to transformation by specific oncogenes and retransformation by 5-azacytidine.

Authors:  D Samid; D M Flessate; R M Friedman
Journal:  Mol Cell Biol       Date:  1987-06       Impact factor: 4.272

2.  The effect of interferons on cellular differentiation.

Authors:  T Moritz; H Kirchner
Journal:  Blut       Date:  1986-11

3.  Induction of c-Ha-ras gene expression by double-stranded RNA and interferon requirement.

Authors:  A Maran; I D Goldberg; B M Steinberg
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

Review 4.  Regulation of cell proliferation and differentiation by interferons.

Authors:  M J Clemens; M A McNurlan
Journal:  Biochem J       Date:  1985-03-01       Impact factor: 3.857

5.  Temperature-sensitive cellular mutant for expression of mRNA from murine retrovirus.

Authors:  H Inoue; S Kizaka; M Yutsudo; A Hakura
Journal:  J Virol       Date:  1988-01       Impact factor: 5.103

6.  Epigenetic inhibition of lysyl oxidase transcription after transformation by ras oncogene.

Authors:  S Contente; K Kenyon; P Sriraman; S Subramanyan; R M Friedman
Journal:  Mol Cell Biochem       Date:  1999-04       Impact factor: 3.396

7.  Interferon alfa-2b in the treatment of chronic granulocytic leukemia.

Authors:  D E Bergsagel; R H Haas; H A Messner
Journal:  Invest New Drugs       Date:  1987       Impact factor: 3.850

8.  Inhibitory effect of interferon on the genetic and oncogenic transformation by viral and cellular genes.

Authors:  M Perucho; M Esteban
Journal:  J Virol       Date:  1985-04       Impact factor: 5.103

9.  Murine gamma interferon inhibits v-mos-induced fibroblast transformation via down regulation of retroviral gene expression.

Authors:  B Seliger; G Kruppa; K Pfizenmaier
Journal:  J Virol       Date:  1987-08       Impact factor: 5.103

10.  Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level.

Authors:  E Knight; E D Anton; D Fahey; B K Friedland; G J Jonak
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205
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