Literature DB >> 6200067

Rat cytomegalovirus: induction of and sensitivity to interferon.

C A Bruggeman, H Schellekens, G Grauls, W M Debie, C P van Boven.   

Abstract

Rat interferon (IFN) in a dose-dependent fashion inhibited the cytopathic effect of rat cytomegalovirus (RCMV) in rat cell cultures. Treatment of Lewis and Brown Norway (BN) rats with intraperitoneal injections of IFN reduced the amount of virus recovered from the spleens at 3 days post infection (p.i.) and from the salivary glands at 10 and 21 days p.i. In cell cultures, RCMV failed to induce detectable amounts of IFN. Small amounts of IFN were detectable in the serum of BN rats at 3 days p.i. In Lewis rats no IFN was found in serum at any time during the first month p.i.

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Year:  1983        PMID: 6200067     DOI: 10.1016/0166-3542(83)90039-6

Source DB:  PubMed          Journal:  Antiviral Res        ISSN: 0166-3542            Impact factor:   5.970


  8 in total

1.  Rat cytomegalovirus gene expression in cardiac allograft recipients is tissue specific and does not parallel the profiles detected in vitro.

Authors:  Daniel N Streblow; Koen W R van Cleef; Craig N Kreklywich; Christine Meyer; Patricia Smith; Victor Defilippis; Finn Grey; Klaus Früh; Robert Searles; Cathrien Bruggeman; Cornelis Vink; Jay A Nelson; Susan L Orloff
Journal:  J Virol       Date:  2007-01-24       Impact factor: 5.103

2.  Cytomegalovirus latency promotes cardiac lymphoid neogenesis and accelerated allograft rejection in CMV naïve recipients.

Authors:  S L Orloff; Y-K Hwee; C Kreklywich; T F Andoh; E Hart; P A Smith; I Messaoudi; D N Streblow
Journal:  Am J Transplant       Date:  2011-01       Impact factor: 8.086

3.  Cytomegalovirus microRNA expression is tissue specific and is associated with persistence.

Authors:  Christine Meyer; Finn Grey; Craig N Kreklywich; Takeshi F Andoh; Rebecca S Tirabassi; Susan L Orloff; Daniel N Streblow
Journal:  J Virol       Date:  2010-10-27       Impact factor: 5.103

4.  Rat cytomegalovirus induces cellular purine and pyrimidine nucleoside kinases in rat embryo fibroblasts and TK- rat-2 cells. Correlations with the antiviral activity of Acyclovir.

Authors:  H Meijer; C A Bruggeman; P H Dormans; C P van Boven
Journal:  Arch Virol       Date:  1985       Impact factor: 2.574

5.  Studies on rat cytomegalovirus induced structural and non-structural proteins present at (immediate-)early and late times of infection.

Authors:  H Meijer; P H Dormans; C P van Boven
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

6.  Cytomegalovirus CC chemokine promotes immune cell migration.

Authors:  Jennifer Vomaske; Michael Denton; Craig Kreklywich; Takeshi Andoh; Jessica M Osborn; Daniel Chen; Ilhem Messaoudi; Susan L Orloff; Daniel N Streblow
Journal:  J Virol       Date:  2012-08-22       Impact factor: 5.103

7.  Cytomegalovirus-mediated upregulation of chemokine expression correlates with the acceleration of chronic rejection in rat heart transplants.

Authors:  Daniel N Streblow; Craig Kreklywich; Qiang Yin; V T De La Melena; Christopher L Corless; Patricia A Smith; Christina Brakebill; Judith W Cook; Cornelis Vink; Cathrien A Bruggeman; Jay A Nelson; Susan L Orloff
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

8.  Rat Cytomegalovirus Vaccine Prevents Accelerated Chronic Rejection in CMV-Naïve Recipients of Infected Donor Allograft Hearts.

Authors:  D N Streblow; Y K Hwee; C N Kreklywich; T Andoh; M Denton; P Smith; E Hart; R Broekel; C Pallett; K Rogers; A D Streblow; M Chuop; A Perry; M Slifka; I Messaoudi; S L Orloff
Journal:  Am J Transplant       Date:  2015-03-12       Impact factor: 8.086

  8 in total

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