Literature DB >> 6199229

Lack of long term effect of p-chlorophenylalanine on brain 5-hydroxytryptamine and electrocortical activity in conscious fetal sheep.

B M Johnston, D W Walker, A R Green.   

Abstract

Daily infusion of p-chlorophenylalanine (p-CPA) into unanesthetized fetal sheep for 3-6 days did not reduce brain 5-hydroxytryptamine (5-HT) concentrations or produce long-term changes in the pattern of electrocortical activity.

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Year:  1984        PMID： 6199229     DOI： 10.1007/bf01947589

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Insomnia following parachlorophenylalanine in the rat.

Authors:  J Mouret; P Bobillier; M Jouvet
Journal:  Eur J Pharmacol       Date:  1968-12       Impact factor: 4.432

2.  Sleep patterns of the monkey and brain serotonin concentration: effect of p-chlorophenylalanine.

Authors:  E D Weitzman; M M Rapport; P McGregor; J Jacoby
Journal:  Science       Date:  1968-06-21       Impact factor: 47.728

Review 3.  Neurophysiology of the states of sleep.

Authors:  M Jouvet
Journal:  Physiol Rev       Date:  1967-04       Impact factor: 37.312

4.  p-Chlorophenylalanine: a specific depletor of brain serotonin.

Authors:  B K Koe; A Weissman
Journal:  J Pharmacol Exp Ther       Date:  1966-12       Impact factor: 4.030

5.  Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain.

Authors:  G Curzon; A R Green
Journal:  Br J Pharmacol       Date:  1970-07       Impact factor: 8.739

6.  Effect of 5-hydroxytryptophan on electrocortical activity and breathing movements of fetal sheep.

Authors:  E J Quilligan; F Clewlow; B M Johnston; D W Walker
Journal:  Am J Obstet Gynecol       Date:  1981-10-01       Impact factor: 8.661

7.  5-hydroxytryptamine, 5-hydroxytryptophan decarboxylase and monoamine oxidase during foetal and postnatal development in the guinea-pig.

Authors:  A Tissari
Journal:  Acta Physiol Scand Suppl       Date:  1966

8.  Changes in breathing, electrocortical and muscle activity in unanaesthetized fetal lambs with age.

Authors:  F Clewlow; G S Dawes; B M Johnston; D W Walker
Journal:  J Physiol       Date:  1983-08       Impact factor: 5.182

9.  Respiratory movements and rapid eye movement sleep in the foetal lamb.

Authors:  G S Dawes; H E Fox; B M Leduc; G C Liggins; R T Richards
Journal:  J Physiol       Date:  1972-01       Impact factor: 5.182

10.  Some pharmacological effects of p-chlorophenylalanine unrelated to tryptophan hydroxylase inhibition.

Authors:  E Marley; J E Whelan
Journal:  Br J Pharmacol       Date:  1976-02       Impact factor: 8.739
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