Literature DB >> 6199217

Binding of [3H]substance P to putative substance P receptors in rat brain membranes.

M H Perrone, R E Diehl, D R Haubrich.   

Abstract

[3H]Substance P was used to label putative substance P receptors in rat brain membranes. [3H]Substance P binding was saturable, reversible, and displaceable by non-radioactive substance P. Association, dissociation and saturation experiments suggest a single site interaction of [3H]substance P to its binding site (k-1/k+1 = 0.56 nM; KD = 0.9 nM, Bmax 86.5 fmol/mg protein.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6199217     DOI: 10.1016/0014-2999(83)90277-7

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  1 in total

1.  Effect of CP-96,345, a nonpeptide substance P receptor antagonist, on salivation in rats.

Authors:  R M Snider; K P Longo; S E Drozda; J A Lowe; S E Leeman
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.