Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Coexistence of helper and suppressor activities in carrier-primed spleen cells.

Literature DB >> 61991

Coexistence of helper and suppressor activities in carrier-primed spleen cells.

Abstract

Both helper and suppressor activities for an in vitro IgG anti-hapten (Lac) response to Lac-HRBC were demonstrated in the same population of carrier (HRBC)-primed spleen cells. The relative radiosensitivity of suppressor activity permitted the selective removal of suppression and the demonstration of help. Both activities appear to be T cell-dependent and antigen-specific. Dilution analysis showed that help and suppression are mediated by distinct populations of cells.

Entities: Gene

Mesh：

Substances：

Year: 1976 PMID： 61991

Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422

Keyword Cloud
Cited

12 in total

1. Lymphocytic choriomeningitis virus-induced immunodepression: inherent defect of B and T lymphocytes.

Authors: M F Saron; B Shidani; M A Nahori; J C Guillon; P Truffa-Bachi
Journal: J Virol Date: 1990-09 Impact factor: 5.103

2. Separation of helper and suppressor T lymphocytes. II. Ly phenotypes and lack of DNA synthesis requirement for the generation of concanavalin A helper and suppressor cells.

Authors: H Y Tse; R W Dutton
Journal: J Exp Med Date: 1977-09-01 Impact factor: 14.307

10. The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine.

Authors: R N Germain; B Benacerraf
Journal: J Exp Med Date: 1978-11-01 Impact factor: 14.307

Coexistence of helper and suppressor activities in carrier-primed spleen cells.

1. Lymphocytic choriomeningitis virus-induced immunodepression: inherent defect of B and T lymphocytes.

2. Separation of helper and suppressor T lymphocytes. II. Ly phenotypes and lack of DNA synthesis requirement for the generation of concanavalin A helper and suppressor cells.

3. B-memory cells can be stimulated by antigen in vitro to become IgG antibody-secreting cells.

4. The in vitro generation of suppressor lymphocytes involves interactions between PNA+ and PNA- thymocyte populations.

5. Production of pemphigus antibody in vitro and analysis of T-cell subsets.

6. The effect of bacterial peptidoglycans on the immune response of hamsters to influenza virus vaccines.

7. Inhibition of lymphocyte proliferation by free fatty acids. III. Modulation of thymus-dependent immune responses.

8. Suppressor-cell functions in bullous pemphigoid.

9. Differential effects of glucocorticosteroids on the functions of helper and suppressor T lymphocytes.

10. The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine.