Literature DB >> 6199080

Apparent sprouting of striatal serotonergic terminals after dopamine-depleting brain lesions in neonatal rats.

M K Stachowiak, J P Bruno, A M Snyder, E M Stricker, M J Zigmond.   

Abstract

Near-total dopamine-depleting brain lesions produced in 3-day-old rats by intracerebroventricular injection of the neurotoxin 6-hydroxydopamine led to pronounced increases in striatal serotonin (5-HT) and 5-hydroxyindoleacetic acid contents 1-8 months later. This effect was associated with an increase in in vitro high affinity 5-HT uptake, suggesting that proliferation of new serotonergic terminals had occurred within the striatum. No such effect was obtained when comparable brain lesions were produced in adult rats.

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Year:  1984        PMID： 6199080     DOI： 10.1016/0006-8993(84)90665-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  33 in total

1.  In vivo studies of the SERT-selective [18F]FPBM and VMAT2-selective [18F]AV-133 radiotracers in a rat model of Parkinson's disease.

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Journal:  Nucl Med Biol       Date:  2010-05       Impact factor: 2.408

Review 2.  Neurobehavioral changes arising from early life dopamine signaling perturbations.

Authors:  Lorena B Areal; Randy D Blakely
Journal:  Neurochem Int       Date:  2020-04-20       Impact factor: 3.921

3.  Plasticity within striatal direct pathway neurons after neonatal dopamine depletion is mediated through a novel functional coupling of serotonin 5-HT2 receptors to the ERK 1/2 map kinase pathway.

Authors:  Pierre Brown; Charles R Gerfen
Journal:  J Comp Neurol       Date:  2006-09-20       Impact factor: 3.215

Review 4.  Monoamine reuptake inhibitors in Parkinson's disease.

Authors:  Philippe Huot; Susan H Fox; Jonathan M Brotchie
Journal:  Parkinsons Dis       Date:  2015-02-25

5.  Dopamine receptor supersensitivity: an outcome and index of neurotoxicity.

Authors:  Richard M Kostrzewa; John P Kostrzewa; Ryszard Brus
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

6.  Unilateral neonatal intracerebroventricular 6-hydroxydopamine administration in rats: I. Effects on spontaneous and drug-induced rotational behaviour and on postmortem monoamine levels.

Authors:  J Luthman; M Herrera-Marschitz; E Lindqvist
Journal:  Psychopharmacology (Berl)       Date:  1994-12       Impact factor: 4.530

7.  Host striatal projections into fetal ventral mesencephalic tissue grafted to the striatum of immature or adult rat.

Authors:  M Chkirate; A Vallée; G Doucet
Journal:  Exp Brain Res       Date:  1993       Impact factor: 1.972

8.  Dopamine receptor agonists regulate levels of the serotonin 5-HT2A receptor and its mRNA in a subpopulation of rat striatal neurons.

Authors:  N Laprade; F Radja; T A Reader; J J Soghomonian
Journal:  J Neurosci       Date:  1996-06-01       Impact factor: 6.167

Review 9.  Mouse models of hypoxanthine phosphoribosyltransferase deficiency.

Authors:  D J Williamson; M L Hooper; D W Melton
Journal:  J Inherit Metab Dis       Date:  1992       Impact factor: 4.982

10.  Behavioral differences between neonatal and adult 6-hydroxydopamine-treated rats to dopamine agonists: relevance to neurological symptoms in clinical syndromes with reduced brain dopamine.

Authors:  G R Breese; A A Baumeister; T J McCown; S G Emerick; G D Frye; K Crotty; R A Mueller
Journal:  J Pharmacol Exp Ther       Date:  1984-11       Impact factor: 4.030
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