Literature DB >> 6197152

Myelin basic protein: a component of circulating immune complexes in multiple sclerosis.

M K Dasgupta, I Catz, K G Warren, T A McPherson, J B Dossetor, P R Carnegie.   

Abstract

Myelin basic protein (MBP) is an antigenic component of circulating immune complexes (CIC) in patients with multiple sclerosis (MS). Immune complexes were isolated from the sera by adsorption to Raji cells and then acid eluted. Final identification of MBP from Raji eluates was done by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) followed by MBP radioimmunoassay (RIA) of gel eluates and by an immunoblot technique.

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Year:  1983        PMID: 6197152     DOI: 10.1017/s0317167100045078

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  4 in total

1.  The role of the thymus in multiple sclerosis.

Authors:  V D'Andrea; G Meco; F Corvese; P F Baselice; V Ambrogi
Journal:  Ital J Neurol Sci       Date:  1989-02

Review 2.  The neuroimmunology of multiple sclerosis: possible roles of T and B lymphocytes in immunopathogenesis.

Authors:  K C O'Connor; A Bar-Or; D A Hafler
Journal:  J Clin Immunol       Date:  2001-03       Impact factor: 8.317

3.  Assessing the values of circulating immune complexes in multiple sclerosis patients following immunomodulator or corticosteroid treatment.

Authors:  Any Docu Axelerad; Alina Zorina Stroe; Anca Elena Gogu; Daniel Docu Axelerad
Journal:  Exp Ther Med       Date:  2021-03-23       Impact factor: 2.447

4.  Autoantibodies to myelin basic protein (MBP) in healthy individuals and in patients with multiple sclerosis: a role in regulating cytokine responses to MBP.

Authors:  Chris J Hedegaard; Ning Chen; Finn Sellebjerg; Per Soelberg Sørensen; R Graham Q Leslie; Klaus Bendtzen; Claus H Nielsen
Journal:  Immunology       Date:  2008-12-18       Impact factor: 7.397

  4 in total

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