Literature DB >> 6196687

CSF and serum interferon in multiple sclerosis: longitudinal study.

R Salonen.   

Abstract

We studied interferon (IFN) in the serum and CSF of 31 patients with multiple sclerosis. The sensitive IFN bioassay required only small volumes and detected IFN levels as low as 0.5 international units/ml (CSF) or 4 international units/ml (serum) of IFN. Two hundred twenty-eight paired CSF/serum samples were tested, and no IFN was found.

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Year:  1983        PMID： 6196687     DOI： 10.1212/wnl.33.12.1604

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  5 in total

Review 1.  Clinical pharmacokinetics of interferons.

Authors:  R J Wills
Journal:  Clin Pharmacokinet       Date:  1990-11       Impact factor: 6.447

2.  Absence of immunoreactive interferon-alpha in CSF from patients with multiple sclerosis.

Authors:  R J Abbott; P D Giles; I Bolderson
Journal:  J Neurol Neurosurg Psychiatry       Date:  1986-01       Impact factor: 10.154

3.  Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma.

Authors:  F M LaFerla; M C Sugarman; T E Lane; M A Leissring
Journal:  J Mol Neurosci       Date:  2000-08       Impact factor: 3.444

Review 4.  Interferons in multiple sclerosis. A review of the evidence.

Authors:  H S Panitch
Journal:  Drugs       Date:  1992-12       Impact factor: 9.546

5.  Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis.

Authors:  T Vartanian; Y Li; M Zhao; K Stefansson
Journal:  Mol Med       Date:  1995-11       Impact factor: 6.354
  5 in total

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