Literature DB >> 6196295

Inhibition of keratinocyte proliferation by extracts of Actinobacillus actinomycetemcomitans.

P R Kamen.   

Abstract

A heat-labile sonic extract of a nonleukotoxic strain of Actinobacillus actinomycetemcomitans caused a dose-dependent inhibition of proliferation of human keratinocytes. Exposure of cells to heat-labile sonic extract for periods as brief as 10 min produced significant suppression of [3H]thymidine uptake 72 h later. I propose that alteration of epithelial barriers may be one pathogenic mechanism of this organism.

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Year:  1983        PMID： 6196295      PMCID： PMC264425          DOI： 10.1128/iai.42.3.1191-1194.1983

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  13 in total

1.  Effects of hyaluronidase on human gingival epithelium.

Authors:  S SCHULTZ-HAUDT; M DEWAR; B G BIBBY
Journal:  Science       Date:  1953-06-12       Impact factor: 47.728

2.  Conversion of stable established gingivitis in the dog into destructive periodontitis.

Authors:  H E Schroeder; J Lindhe
Journal:  Arch Oral Biol       Date:  1975-12       Impact factor: 2.633

3.  Epithelial changes in gingivitis. An electron microscopy study.

Authors:  H Thilander
Journal:  J Periodontal Res       Date:  1968       Impact factor: 4.419

4.  The effects of bacterial sonicates on human keratinizing stratified squamous epithelium in vitro.

Authors:  P R Kamen
Journal:  J Periodontal Res       Date:  1981-05       Impact factor: 4.419

5.  Release of toxic microvesicles by Actinobacillus actinomycetemcomitans.

Authors:  A Nowotny; U H Behling; B Hammond; C H Lai; M Listgarten; P H Pham; F Sanavi
Journal:  Infect Immun       Date:  1982-07       Impact factor: 3.441

6.  Histological and ultrastructural characteristics of the periodontal syndrome in the rice rat. I. General light microscopic observations and ultrastructural observations of initial inflammatory changes.

Authors:  M I Ryder
Journal:  J Periodontal Res       Date:  1980-09       Impact factor: 4.419

7.  Interaction of inflammatory cells and oral microorganisms. VIII. Detection of leukotoxic activity of a plaque-derived gram-negative microorganism.

Authors:  P Baehni; C C Tsai; W P McArthur; B F Hammond; N S Taichman
Journal:  Infect Immun       Date:  1979-04       Impact factor: 3.441

8.  Conversion of chronic gingivitis to periodontitis in squirrel monkeys.

Authors:  L Heijl; B R Rifkin; H A Zander
Journal:  J Periodontol       Date:  1976-12       Impact factor: 6.993

9.  Inhibition of fibroblast proliferation by Actinobacillus actinomycetemcomitans.

Authors:  B J Shenker; M E Kushner; C C Tsai
Journal:  Infect Immun       Date:  1982-12       Impact factor: 3.441

10.  Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells.

Authors:  J G Rheinwald; H Green
Journal:  Cell       Date:  1975-11       Impact factor: 41.582
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  9 in total

1.  Prevalence of cytolethal distending toxin production in periodontopathogenic bacteria.

Authors:  Ryousuke Yamano; Masaru Ohara; Shuichi Nishikubo; Tamaki Fujiwara; Toru Kawamoto; Yoko Ueno; Hitoshi Komatsuzawa; Katsuji Okuda; Hidemi Kurihara; Hidekazu Suginaka; Eric Oswald; Kazuo Tanne; Motoyuki Sugai
Journal:  J Clin Microbiol       Date:  2003-04       Impact factor: 5.948

2.  The cell cycle-specific growth-inhibitory factor produced by Actinobacillus actinomycetemcomitans is a cytolethal distending toxin.

Authors:  M Sugai; T Kawamoto; S Y Pérès; Y Ueno; H Komatsuzawa; T Fujiwara; H Kurihara; H Suginaka; E Oswald
Journal:  Infect Immun       Date:  1998-10       Impact factor: 3.441

3.  Immunosuppressive properties of Actinobacillus actinomycetemcomitans leukotoxin.

Authors:  G Rabie; E T Lally; B J Shenker
Journal:  Infect Immun       Date:  1988-01       Impact factor: 3.441

4.  Identification of a cytolethal distending toxin gene locus and features of a virulence-associated region in Actinobacillus actinomycetemcomitans.

Authors:  M P Mayer; L C Bueno; E J Hansen; J M DiRienzo
Journal:  Infect Immun       Date:  1999-03       Impact factor: 3.441

5.  Conjugal transfer of broad-host-range incompatibility group P and Q plasmids from Escherichia coli to Actinobacillus actinomycetemcomitans.

Authors:  P Goncharoff; J K Yip; H Wang; H C Schreiner; J A Pai; D Furgang; R H Stevens; D H Figurski; D H Fine
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

6.  A bacteriocin of Actinobacillus actinomycetemcomitans.

Authors:  B F Hammond; S E Lillard; R H Stevens
Journal:  Infect Immun       Date:  1987-03       Impact factor: 3.441

7.  Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces apoptosis in nonproliferating macrophages by a phosphatase-independent mechanism.

Authors:  Shira D P Rabin; Jared G Flitton; Donald R Demuth
Journal:  Infect Immun       Date:  2009-05-26       Impact factor: 3.441

8.  Characterization of an antiproliferative surface-associated protein from Actinobacillus actinomycetemcomitans which can be neutralized by sera from a proportion of patients with localized juvenile periodontitis.

Authors:  P A White; M Wilson; S P Nair; A C Kirby; K Reddi; B Henderson
Journal:  Infect Immun       Date:  1995-07       Impact factor: 3.441

9.  Effect of total sonicated Aggregatibacter actinomycetemcomitans fragments on gingival stem/progenitor cells.

Authors:  K Fawzy El-Sayed; C Graetz; T Köhnlein; M Mekhemar; C Dörfer
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2018-09-01
  9 in total

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