Literature DB >> 6196191

Coronavirus mRNA synthesis involves fusion of non-contiguous sequences.

W Spaan, H Delius, M Skinner, J Armstrong, P Rottier, S Smeekens, B A van der Zeijst, S G Siddell.   

Abstract

Positive-stranded genomic RNA of coronavirus MHV and its six subgenomic mRNAs are synthesized in the cytoplasm of the host cell. The mRNAs are composed of leader and body sequences which are non-contiguous on the genome and are fused together in the cytoplasm by a mechanism which appears to involve an unusual and specific 'polymerase jumping' event.

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Year:  1983        PMID： 6196191      PMCID： PMC555368     

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  34 in total

1.  Length measurements of RNA synthesized in vitro by Escherichia coli RNA polymerase.

Authors:  H Delius; H Westphal; N Axelrod
Journal:  J Mol Biol       Date:  1973-03-15       Impact factor: 5.469

2.  DNA sequence analysis by primed synthesis.

Authors:  A J Smith
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

3.  Sequences from the beginning of the fiber messenger RNA of adenovirus-2.

Authors:  B S Zain; R J Roberts
Journal:  J Mol Biol       Date:  1979-06-25       Impact factor: 5.469

4.  3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors.

Authors:  D Zimmern; P Kaesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-09       Impact factor: 11.205

5.  Electron microscopic mapping and sequence analysis of the terminator for the early message of E. coli phage T7.

Authors:  H Priess; B Koller; B Hess; H Delius
Journal:  Mol Gen Genet       Date:  1980-04

6.  Sequence of chicken ovalbumin mRNA.

Authors:  L McReynolds; B W O'Malley; A D Nisbet; J E Fothergill; D Givol; S Fields; M Robertson; G G Brownlee
Journal:  Nature       Date:  1978-06-29       Impact factor: 49.962

7.  The replication of murine coronaviruses in enucleated cells.

Authors:  K C Wilhelmsen; J L Leibowitz; C W Bond; J A Robb
Journal:  Virology       Date:  1981-04-15       Impact factor: 3.616

8.  Coronavirus JHM: cell-free synthesis of structural protein p60.

Authors:  S G Siddell; H Wege; A Barthel; V ter Meulen
Journal:  J Virol       Date:  1980-01       Impact factor: 5.103

9.  Coronavirus JHM: nucleotide sequence of the mRNA that encodes nucleocapsid protein.

Authors:  M A Skinner; S G Siddell
Journal:  Nucleic Acids Res       Date:  1983-08-11       Impact factor: 16.971

10.  Isolation and identification of virus-specific mRNAs in cells infected with mouse hepatitis virus (MHV-A59).

Authors:  W J Spaan; P J Rottier; M C Horzinek; B A van der Zeijst
Journal:  Virology       Date:  1981-01-30       Impact factor: 3.616
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  133 in total

1.  Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences.

Authors:  G van Marle; J C Dobbe; A P Gultyaev; W Luytjes; W J Spaan; E J Snijder
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-12       Impact factor: 11.205

2.  A phylogenetically conserved hairpin-type 3' untranslated region pseudoknot functions in coronavirus RNA replication.

Authors:  G D Williams; R Y Chang; D A Brian
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

3.  Subgenomic mRNA regulation by a distal RNA element in a (+)-strand RNA virus.

Authors:  G Zhang; V Slowinski; K A White
Journal:  RNA       Date:  1999-04       Impact factor: 4.942

4.  Downstream sequences influence the choice between a naturally occurring noncanonical and closely positioned upstream canonical heptameric fusion motif during bovine coronavirus subgenomic mRNA synthesis.

Authors:  A Ozdarendeli; S Ku; S Rochat; G D Williams; S D Senanayake; D A Brian
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

5.  Characterization of the coronavirus M protein and nucleocapsid interaction in infected cells.

Authors:  K Narayanan; A Maeda; J Maeda; S Makino
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

6.  Genetic manipulation of arterivirus alternative mRNA leader-body junction sites reveals tight regulation of structural protein expression.

Authors:  A O Pasternak; A P Gultyaev; W J Spaan; E J Snijder
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

7.  Regulation of relative abundance of arterivirus subgenomic mRNAs.

Authors:  Alexander O Pasternak; Willy J M Spaan; Eric J Snijder
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

8.  A domain at the 3' end of the polymerase gene is essential for encapsidation of coronavirus defective interfering RNAs.

Authors:  R G van der Most; P J Bredenbeek; W J Spaan
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

9.  Coronavirus leader RNA regulates and initiates subgenomic mRNA transcription both in trans and in cis.

Authors:  X Zhang; C L Liao; M M Lai
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

10.  The murine coronavirus nucleocapsid gene is a determinant of virulence.

Authors:  Timothy J Cowley; Simon Y Long; Susan R Weiss
Journal:  J Virol       Date:  2009-12-09       Impact factor: 5.103
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