Literature DB >> 6196148

The elastase-antielastase hypothesis of the pathogenesis of emphysema.

P J Stone.   

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Year:  1983        PMID: 6196148

Source DB:  PubMed          Journal:  Clin Chest Med        ISSN: 0272-5231            Impact factor:   2.878


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  9 in total

1.  Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase.

Authors:  R C Hubbard; F Ogushi; G A Fells; A M Cantin; S Jallat; M Courtney; R G Crystal
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

Review 2.  Entropic elastic processes in protein mechanisms. II. Simple (passive) and coupled (active) development of elastic forces.

Authors:  D W Urry
Journal:  J Protein Chem       Date:  1988-04

Review 3.  Bioactive extracellular matrix fragments in lung health and disease.

Authors:  Amit Gaggar; Nathaniel Weathington
Journal:  J Clin Invest       Date:  2016-09-01       Impact factor: 14.808

4.  Oxidative regulation of neutrophil elastase-alpha-1-proteinase inhibitor interactions.

Authors:  P J Ossanna; S T Test; N R Matheson; S Regiani; S J Weiss
Journal:  J Clin Invest       Date:  1986-06       Impact factor: 14.808

5.  Elastin in a neonatal rat smooth muscle cell culture has greatly decreased susceptibility to proteolysis by human neutrophil elastase. An in vitro model of elastolytic injury.

Authors:  P J Stone; M P McMahon; S M Morris; J D Calore; C Franzblau
Journal:  In Vitro Cell Dev Biol       Date:  1987-10

6.  Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.

Authors:  F Ogushi; G A Fells; R C Hubbard; S D Straus; R G Crystal
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

7.  Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals.

Authors:  J F Mornex; A Chytil-Weir; Y Martinet; M Courtney; J P LeCocq; R G Crystal
Journal:  J Clin Invest       Date:  1986-06       Impact factor: 14.808

8.  Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.

Authors:  F Ogushi; R C Hubbard; C Vogelmeier; G A Fells; R G Crystal
Journal:  J Clin Invest       Date:  1991-03       Impact factor: 14.808

9.  Gene Profiles in a Smoke-Induced COPD Mouse Lung Model Following Treatment with Mesenchymal Stem Cells.

Authors:  You-Sun Kim; Nurdan Kokturk; Ji-Young Kim; Sei Won Lee; Jaeyun Lim; Soo Jin Choi; Wonil Oh; Yeon-Mok Oh
Journal:  Mol Cells       Date:  2016-10-31       Impact factor: 5.034

  9 in total

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