Literature DB >> 6196085

In vitro myelin basic protein synthesis in the PNS and CNS of myelin deficient (mld) mutant mice.

H Ginalski-Winkelmann, G Almazan, J M Matthieu.   

Abstract

The CNS of the mutant mld has a severe myelin deficit. In contrast, myelination is normal in the PNS. Previous studies showed that myelin basic proteins (MBP) are practically missing in mld CNS and PNS tissues. Using an in vitro system and immunoprecipitation, we present evidence that MBP synthesis is repressed in the PNS and in the CNS of mld mutants.

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Year:  1983        PMID： 6196085     DOI： 10.1016/0006-8993(83)90952-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  4 in total

Review 1.  Cellular and molecular aspects of myelin protein gene expression.

Authors:  A T Campagnoni; W B Macklin
Journal:  Mol Neurobiol       Date:  1988       Impact factor: 5.590

2.  Post-transcriptional events are responsible for low expression of myelin basic protein in myelin deficient mice: role of natural antisense RNA.

Authors:  M Tosic; A Roach; J C de Rivaz; M Dolivo; J M Matthieu
Journal:  EMBO J       Date:  1990-02       Impact factor: 11.598

3.  Gene organization and transcription of duplicated MBP genes of myelin deficient (shi(mld)) mutant mouse.

Authors:  H Okano; T Tamura; M Miura; A Aoyama; K Ikenaka; M Oshimura; K Mikoshiba
Journal:  EMBO J       Date:  1988-01       Impact factor: 11.598

4.  Myelin instability and oligodendrocyte metabolism in myelin-deficient mutant mice.

Authors:  J M Matthieu; J M Roch; F X Omlin; I Rambaldi; G Almazan; P E Braun
Journal:  J Cell Biol       Date:  1986-12       Impact factor: 10.539
  4 in total

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