Literature DB >> 6193819

Interaction of chromosomal stains with DNA. An electrofluorescence study.

B R Jennings, P J Ridler.   

Abstract

A novel fluorescence procedure has been used to study the binding characteristics of DNA with three modern fluorochromes currently used in chromosome cytochemistry. The transient changes in the polarised components of fluorescence have been recorded for dye-tagged DNA solutions when subjected to short duration electric pulses. From these data, it has been inferred that, like ethidium bromide, berberine sulphate and quinacrine mustard both intercalate the DNA structure whilst the bi-benzimidazole derivative Hoechst 33258 binds with a distinctively different geometry, probably within the helical grooves.

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Year:  1983        PMID： 6193819     DOI： 10.1007/bf00535543

Source DB:  PubMed          Journal:  Biophys Struct Mech        ISSN： 0340-1057


  11 in total

1.  Fluorometric properties of the bibenzimidazole derivative Hoechst 33258, a fluorescent probe specific for AT concentration in chromosomal DNA.

Authors:  B Weisblum; E Haenssler
Journal:  Chromosoma       Date:  1974       Impact factor: 4.316

2.  Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Authors:  S A Latt
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

3.  Staining of constitutive heterochromatin in mammalian chromosomes with a new fluorochrome.

Authors:  I Hilwig; A Gropp
Journal:  Exp Cell Res       Date:  1972-11       Impact factor: 3.905

4.  Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes.

Authors:  T Caspersson; L Zech; E J Modest; G E Foley; U Wagh; E Simonsson
Journal:  Exp Cell Res       Date:  1969-11       Impact factor: 3.905

5.  Transient electric dichroism studies of the structure of the DNA complex with intercalated drugs.

Authors:  M Hogan; N Dattagupta; D M Crothers
Journal:  Biochemistry       Date:  1979-01-23       Impact factor: 3.162

Review 6.  Fine structure of chromosomes as revealed by fluorescence analysis.

Authors:  J Moutschen
Journal:  Prog Biophys Mol Biol       Date:  1976       Impact factor: 3.667

7.  Electrically induced fluorescence as a method for studying benzo[a]pyrene binding to DNA.

Authors:  P J Ridler; B R Jennings
Journal:  FEBS Lett       Date:  1982-03-08       Impact factor: 4.124

8.  The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability.

Authors:  T Caspersson; G Lomakka; L Zech
Journal:  Hereditas       Date:  1972       Impact factor: 3.271

9.  Quinacrine, a chromosome stain specific for deoxyadenylate-deoxythymidylaterich regions in DNA.

Authors:  B Weisblum; P L De Haseth
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

10.  Mechanisms of chromosome banding. VIII. Hoechst 33258-DNA interaction.

Authors:  D E Comings
Journal:  Chromosoma       Date:  1975-10-14       Impact factor: 4.316
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  6 in total

1.  Multidrug pump inhibitors uncover remarkable activity of plant antimicrobials.

Authors:  George Tegos; Frank R Stermitz; Olga Lomovskaya; Kim Lewis
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

2.  Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor.

Authors:  F R Stermitz; P Lorenz; J N Tawara; L A Zenewicz; K Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-15       Impact factor: 11.205

3.  The "interceptor" properties of chlorophyllin measured within the three-component system: intercalator-DNA-chlorophyllin.

Authors:  Monika Pietrzak; Zbigniew Wieczorek; Jolanta Wieczorek; Zbigniew Darzynkiewicz
Journal:  Biophys Chem       Date:  2006-04-06       Impact factor: 2.352

4.  A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.

Authors:  Vito W Rebecca; Michael C Nicastri; Noel McLaughlin; Colin Fennelly; Quentin McAfee; Amruta Ronghe; Michel Nofal; Chun-Yan Lim; Eric Witze; Cynthia I Chude; Gao Zhang; Gretchen M Alicea; Shengfu Piao; Sengottuvelan Murugan; Rani Ojha; Samuel M Levi; Zhi Wei; Julie S Barber-Rotenberg; Maureen E Murphy; Gordon B Mills; Yiling Lu; Joshua Rabinowitz; Ronen Marmorstein; Qin Liu; Shujing Liu; Xiaowei Xu; Meenhard Herlyn; Roberto Zoncu; Donita C Brady; David W Speicher; Jeffrey D Winkler; Ravi K Amaravadi
Journal:  Cancer Discov       Date:  2017-09-12       Impact factor: 39.397

5.  Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel.

Authors:  H L Lin; T Y Liu; C W Wu; C W Chi
Journal:  Br J Cancer       Date:  1999-10       Impact factor: 7.640

6.  A quaternary ammonium silane antimicrobial triggers bacterial membrane and biofilm destruction.

Authors:  Umer Daood; Jukka P Matinlinna; Malikarjuna Rao Pichika; Kit-Kay Mak; Venkateshbabu Nagendrababu; Amr S Fawzy
Journal:  Sci Rep       Date:  2020-07-03       Impact factor: 4.379
  6 in total

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