Literature DB >> 6193003

Effect of acute and chronic 17 beta-estradiol treatment on serotonin and 5-hydroxyindole acetic acid content of discrete brain nuclei of ovariectomized rat.

T Di Paolo, M Diagle, V Picard, N Barden.   

Abstract

Increased serotonin content of the dorsal raphe nucleus and of the substantia nigra were seen following acute (12 h or 24 h) administration of 17 beta-estradiol to ovariectomized rats. No changes were seen in numerous other nuclei of forebrain or hindbrain, and no changes occurred during chronic (1 month) estradiol administration. Changes in the concentration of the major serotonin metabolite, 5-hydroxyindole acetic acid, paralleled those of serotonin. These results show that, under precisely defined conditions and in specific locations only, estradiol can modulate serotonergic neuronal systems.

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Year:  1983        PMID: 6193003     DOI: 10.1007/bf00236804

Source DB:  PubMed          Journal:  Exp Brain Res        ISSN: 0014-4819            Impact factor:   1.972


  24 in total

1.  Proceedings: Variations in the concentrations of monamines and their metabolites in eight regions of rat brain during the oestrous cycle: a basis for interactions between hormones and psychotropic drugs.

Authors:  J M Fludder; S R Tonge
Journal:  J Pharm Pharmacol       Date:  1975-12       Impact factor: 3.765

2.  Lack of effect of various endocrine manipulations on tryptophan hydroxylase activity of individual nuclei of the hypothalamus, limbic system, and midbrain of the rat.

Authors:  J S Kizer; M Palkovits; I J Kopin; J M Saavedra; M J Brownstein
Journal:  Endocrinology       Date:  1976-03       Impact factor: 4.736

3.  Changes in brain monoamine concentrations during the oestrous cycle in the mouse: possible pharmacological implications.

Authors:  P M Greengrass; S R Tonge
Journal:  J Pharm Pharmacol       Date:  1971-11       Impact factor: 3.765

4.  Further studies on monoamine metabolism in three regions of mouse brain during pregnancy: monoamine metabolite concentrations and the effects of injected hormones.

Authors:  P M Greengrass; S R Tonge
Journal:  Arch Int Pharmacodyn Ther       Date:  1974-11

Review 5.  The brain as a target for steroid hormone action.

Authors:  B S McEwen; P G Davis; B Parsons; D W Pfaff
Journal:  Annu Rev Neurosci       Date:  1979       Impact factor: 12.449

6.  Isolated removal of hypothalamic or other brain nuclei of the rat.

Authors:  M Palkovits
Journal:  Brain Res       Date:  1973-09-14       Impact factor: 3.252

7.  Modulation by estradiol of serotonin receptors in brain.

Authors:  A Biegon; B S McEwen
Journal:  J Neurosci       Date:  1982-02       Impact factor: 6.167

Review 8.  Serotonin and central nervous system function.

Authors:  T N Chase; D L Murphy
Journal:  Annu Rev Pharmacol       Date:  1973       Impact factor: 13.820

9.  Effects of ovarian hormones on levels of luteinizing hormone in plasma and on serotonin concentrations in discrete brain nuclei.

Authors:  W R Crowley; T L O'Donohue; E A Muth; D M Jacobowitz
Journal:  Brain Res Bull       Date:  1979 Jul-Aug       Impact factor: 4.077

10.  Effects of ovarian steroids on serotonin metabolism within grossly dissected and microdissected brain regions of the ovariectomized rat.

Authors:  R I Cone; G A Davis; R W Goy
Journal:  Brain Res Bull       Date:  1981-12       Impact factor: 4.077

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  10 in total

Review 1.  Psychotropic properties of ovarian estrogens (review).

Authors:  E B Arushanyan; G K Borovkova
Journal:  Neurosci Behav Physiol       Date:  1989 Jan-Feb

Review 2.  Ovarian steroids and serotonin neural function.

Authors:  C L Bethea; M Pecins-Thompson; W E Schutzer; C Gundlah; Z N Lu
Journal:  Mol Neurobiol       Date:  1998-10       Impact factor: 5.590

Review 3.  Atrial fibrillation.

Authors:  Bianca J J M Brundel; Xun Ai; Mellanie True Hills; Myrthe F Kuipers; Gregory Y H Lip; Natasja M S de Groot
Journal:  Nat Rev Dis Primers       Date:  2022-04-07       Impact factor: 52.329

4.  Effects of sex and estrogen on behavioral sensitization to cocaine in rats.

Authors:  Ming Hu; Jill B Becker
Journal:  J Neurosci       Date:  2003-01-15       Impact factor: 6.167

5.  Prenatal alcohol exposure results in long-term serotonin neuron deficits in female rats: modulatory role of ovarian steroids.

Authors:  Joanna H Sliwowska; Hyun Jung Song; Tamara Bodnar; Joanne Weinberg
Journal:  Alcohol Clin Exp Res       Date:  2013-08-05       Impact factor: 3.455

6.  Acquisition of cocaine self-administration in ovariectomized female rats: effect of estradiol dose or chronic estradiol administration.

Authors:  Ming Hu; Jill B Becker
Journal:  Drug Alcohol Depend       Date:  2007-12-03       Impact factor: 4.492

7.  Modulation of human serotonin transporter expression by 5-HTTLPR in colon cells.

Authors:  Anchalee Prasansuklab; Yong Poovorawan; Tewin Tencomnao
Journal:  Int J Mol Sci       Date:  2011-10-10       Impact factor: 5.923

Review 8.  The Antidepressant-like Effects of Estrogen-mediated Ghrelin.

Authors:  Pu Wang; Changhong Liu; Lei Liu; Xingyi Zhang; Bingzhong Ren; Bingjin Li
Journal:  Curr Neuropharmacol       Date:  2015       Impact factor: 7.363

9.  Ghrelin produces antidepressant-like effect in the estrogen deficient mice.

Authors:  Jie Fan; Bing Jin Li; Xue Feng Wang; Li Li Zhong; Ran Ji Cui
Journal:  Oncotarget       Date:  2017-08-01

10.  X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy.

Authors:  Cory A Massey; Samantha J Thompson; Ryan W Ostrom; Janice Drabek; Olafur A Sveinsson; Torbjörn Tomson; Elisabeth A Haas; Othon J Mena; Alica M Goldman; Jeffrey L Noebels
Journal:  Brain Commun       Date:  2021-07-09
  10 in total

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