[Characteristics of hyperchromic neurons from a focus of local cortical destruction].

Using the Bernhard method of differential staining of ribonucleoproteins the sequence of neuronal destruction by a hyperchromic manner has been demonstrated in the focus of local destruction in the rat brain. This process is marked by a decrease of nuclear synthetic activity, inhibition of the nuclear-cytoplasmic transport, transition of the nucleus components to a metabolically inert state followed by the hydrolysis of the nuclear ribonucleoprotein particles, and destruction of cytoplasmic mitochondria. The processes of neuronal destruction by a hyperchromic manner are culminated in neuronophagia on the part of the oligodendroglia.