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Literature DB >> 6192441

A precise termination site in the mouse beta major-globin transcription unit.

Abstract

Nascent labeled RNA from induced, globin-producing mouse erythroleukemia cells was hybridized to cloned regions of the beta major-globin gene. Transcription ceases about 1,000 bases downstream from the poly(A) site as indicated by protection from nuclease digestion of a discrete-sized RNA fragment that it shorter than the protecting cloned DNA fragment. This defines an apparently unique termination site for a protein-coding gene that is transcribed by RNA polymerase II.

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Year: 1983 PMID： 6192441 PMCID： PMC384110 DOI： 10.1073/pnas.80.15.4694

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

30 in total

1. Transcription pattern of in vivo-labeled late simian virus 40 RNA: equimolar transcription beyond the mRNA 3' terminus.

Authors: J P Ford; M T Hsu
Journal: J Virol Date: 1978-12 Impact factor: 5.103

2. The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.

Authors: D A Konkel; S M Tilghman; P Leder
Journal: Cell Date: 1978-12 Impact factor: 41.582

3. The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.

Authors: D A Konkel; J V Maizel; P Leder
Journal: Cell Date: 1979-11 Impact factor: 41.582

4. Promoter sequences of eukaryotic protein-coding genes.

Authors: J Corden; B Wasylyk; A Buchwalder; P Sassone-Corsi; C Kedinger; P Chambon
Journal: Science Date: 1980-09-19 Impact factor: 47.728

5. Template-determined, variable rate of RNA chain elongation.

Authors: D R Mills; C Dobkin; F R Kramer
Journal: Cell Date: 1978-10 Impact factor: 41.582

6. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

Authors: J L Manley; A Fire; A Cano; P A Sharp; M L Gefter
Journal: Proc Natl Acad Sci U S A Date: 1980-07 Impact factor: 11.205

7. Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system.

Authors: D S Luse; R G Roeder
Journal: Cell Date: 1980-07 Impact factor: 41.582

8. The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site.

Authors: N W Fraser; J R Nevins; E Ziff; J E Darnell
Journal: J Mol Biol Date: 1979-04-25 Impact factor: 5.469

9. Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA.

Authors: P A Weil; D S Luse; J Segall; R G Roeder
Journal: Cell Date: 1979-10 Impact factor: 41.582

10. Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure.

Authors: F C Kafatos; C W Jones; A Efstratiadis
Journal: Nucleic Acids Res Date: 1979-11-24 Impact factor: 16.971

19 in total

1. Look before you quote.

Authors: K Dickerson; P Hewitt
Journal: Br Med J (Clin Res Ed) Date: 1986-10-18

2. Transcription of the alpha globin gene domain in normal and AEV-transformed chicken erythroblasts: mapping of giant globin-specific RNA including embryonic and adult genes.

Authors: F Broders; K Scherrer
Journal: Mol Gen Genet Date: 1987-09

A precise termination site in the mouse beta major-globin transcription unit.

1. Transcription pattern of in vivo-labeled late simian virus 40 RNA: equimolar transcription beyond the mRNA 3' terminus.

2. The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.

3. The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.

4. Promoter sequences of eukaryotic protein-coding genes.

5. Template-determined, variable rate of RNA chain elongation.

6. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

7. Accurate transcription initiation on a purified mouse beta-globin DNA fragment in a cell-free system.

8. The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site.

9. Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA.

10. Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure.

1. Look before you quote.

2. Transcription of the alpha globin gene domain in normal and AEV-transformed chicken erythroblasts: mapping of giant globin-specific RNA including embryonic and adult genes.

3. A specific DNA sequence controls termination of transcription in the gastrin gene.

4. Sequence signals which may be required for efficient formation of mRNA 3' termini.

5. Transcription unit mapping in adenovirus: regions of termination.

6. Unusual organization of the ilvIH promoter of Escherichia coli.

7. mRNA transcripts of several plant genes are polyadenylated at multiple sites in vivo.

8. Requirement for the 3' flanking region of the bovine growth hormone gene for accurate polyadenylylation.

9. Specific termination of in vitro transcription by calf thymus RNA polymerase III.

10. Sequences responsible for transcription termination on a gene segment in Saccharomyces cerevisiae.