Literature DB >> 619120

Determination of time course of tablet disintegration II: Method using continuous functions.

K G Nelson, L Y Wang.   

Abstract

An analysis of the disintegration-dissolution sequence of drug release from a tablet leads to a mathematical expression relating disintegration to the dissolution profile of the tablet and the dissolution rate of the primary drug particles in the tablet. The equation describing the disintegration of an acetaminophen tablet is determined to demonstrate the application of the theory.

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Year:  1978        PMID： 619120     DOI： 10.1002/jps.2600670122

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  4 in total

1.  Concentration profile for the dissolution of drug tablets undergoing simultaneous degradation.

Authors:  H S Chen; S Y Chang; T L Evans; J F Gross
Journal:  J Pharmacokinet Biopharm       Date:  1980-12

2.  Effect of Porosity on Strength Distribution of Microcrystalline Cellulose.

Authors:  Özgür Keleṣ; Nicholas P Barcenas; Daniel H Sprys; Keith J Bowman
Journal:  AAPS PharmSciTech       Date:  2015-05-29       Impact factor: 3.246

3.  Formulation and evaluation of mucoadhesive glipizide microspheres.

Authors:  Jayvadan K Patel; Rakesh P Patel; Avani F Amin; Madhabhai M Patel
Journal:  AAPS PharmSciTech       Date:  2005-09-20       Impact factor: 3.246

4.  Formulation and optimization of sustained release Stavudine microspheres using response surface methodology.

Authors:  Sanjay Dey; Soumen Pramanik; Ananya Malgope
Journal:  ISRN Pharm       Date:  2011-06-28
  4 in total

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