| Literature DB >> 6190795 |
A J Giannini, S Castellani, A E Dvoredsky.
Abstract
Five cases are described that offer evidence for the existence of the "serotonin irritation syndrome," an anxiety state associated with high cation environments, elevated serum serotonin, and decreased urinary 5-hydroxyindoleacetic acid. The therapeutic response and reduction in serum serotonin after treatment with methysergide and/or removal from the high-cation environment support a serotonergic basis of the anxiety.Entities:
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Year: 1983 PMID： 6190795
Source DB: PubMed Journal: J Clin Psychiatry ISSN： 0160-6689 Impact factor: 4.384