Literature DB >> 6190661

HLA class I genes integrated into murine cells are inducible by interferon.

F Rosa, P P Le Bouteiller, A Abadie, Z Mishal, F A Lemonnier, D Bourrel, M Lamotte, J Kalil, B Jordan, M Fellous.   

Abstract

In human cells treated with interferon, there is an increase in the amount of HLA-A, B, C mRNA and, to a lower extent, membrane-bound antigen. However, the mechanism of this mRNA enhancement is still unknown. Using mouse L cells transfected with a unique class I HLA gene, we were able to show that both the related HLA mRNA and protein are increased after murine but not human interferon treatment. Moreover, the discrepancy between interferon-directed HLA mRNA and protein enhancement is also observed. The mouse transfected cells allowed us to study more precisely the origin of this discrepancy.

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Year:  1983        PMID: 6190661     DOI: 10.1002/eji.1830130612

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN: 0014-2980            Impact factor:   5.532


  17 in total

1.  Differential regulation of HLA class I genes by interferon.

Authors:  H Schmidt; V Gekeler; H Haas; G Engler-Blum; I Steiert; H Probst; C A Müller
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

2.  Overexpression of class I major histocompatibility complex accompanies insulitis in the non-obese diabetic mouse and is prevented by anti-interferon-gamma antibody.

Authors:  T W Kay; I L Campbell; L Oxbrow; L C Harrison
Journal:  Diabetologia       Date:  1991-11       Impact factor: 10.122

3.  A transcription factor interacting with the class I gene enhancer is inactive in tumorigenic cell lines which suppress major histocompatibility complex class I genes.

Authors:  U Henseling; W Schmidt; H R Schöler; P Gruss; A K Hatzopoulos
Journal:  Mol Cell Biol       Date:  1990-08       Impact factor: 4.272

4.  Transcriptional regulation of the MHC class I HLA-A11 promoter by the zinc finger protein ZFX.

Authors:  M L'Haridon; P Paul; J G Xerri; H Dastot; C Dolliger; M Schmid; N de Angelis; L Grollet; F Sigaux; L Degos; C Gazin
Journal:  Nucleic Acids Res       Date:  1996-05-15       Impact factor: 16.971

5.  Expression of an HLA-Bw6-related specificity by the HLA-Cw3 molecule.

Authors:  C Layet; T Delovitch; P Ferrier; D H Caillol; B R Jordan; F A Lemonnier
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

6.  Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.

Authors:  J M Boss; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

7.  A transcriptional enhancer and an interferon-responsive sequence in major histocompatibility complex class I genes.

Authors:  J Vogel; M Kress; G Khoury; G Jay
Journal:  Mol Cell Biol       Date:  1986-10       Impact factor: 4.272

8.  Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

Authors:  T Collins; A J Korman; C T Wake; J M Boss; D J Kappes; W Fiers; K A Ault; M A Gimbrone; J L Strominger; J S Pober
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

9.  Autocrine induction of major histocompatibility complex class I antigen expression results from induction of beta interferon in oncogene-transformed BALB/c-3T3 cells.

Authors:  M K Offermann; D V Faller
Journal:  Mol Cell Biol       Date:  1989-05       Impact factor: 4.272

10.  Tumor necrosis factor alpha stimulates expression of adenovirus early region 3 proteins: implications for viral persistence.

Authors:  H Körner; U Fritzsche; H G Burgert
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

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