Literature DB >> 6190430

[Presence of 2 different epitopes on the human beta 2-microglobulin defined by monoclonal antibodies].

D Crevat, J Kalil, F Rosa, M Fellous.   

Abstract

Two monoclonal antibodies recognizing monomorphic determinants on class I antigens of MHC were characterized. They were shown to recognize beta 2m by cytotoxicity inhibition studies. The epitopes recognized were different, as assayed by cross-inhibition and phylogenetical studies. One antibody recognized free as well as HLA-associated beta 2m. The other reacted with a conformational epitope which was well conserved during evolution.

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Year:  1983        PMID： 6190430

Source DB:  PubMed          Journal:  Ann Immunol (Paris)        ISSN： 0300-4910


  4 in total

1.  Serological expression after sequential double transfection with purified HLA-A11 gene of mouse fibroblasts carrying human beta-2 microglobulin.

Authors:  P Paul; V Lepage; B Sayagh; J J Metzger; M Pla; L Boumsell; C Douay; D Cohen; J Colombani; J Dausset
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

2.  Thymoma epithelial cells secrete thymic hormone but do not express class II antigens of the major histocompatibility complex.

Authors:  W Savino; G Manganella; J M Verley; A Wolff; S Berrih; P Levasseur; J P Binet; M Dardenne; J F Bach
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

3.  In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals.

Authors:  Leo Kei Iwai; Márcia Yoshida; John Sidney; Maria Aparecida Shikanai-Yasuda; Anna Carla Goldberg; Maria Aparecida Juliano; Jurgen Hammer; Luiz Juliano; Alessandro Sette; Jorge Kalil; Luiz Rodolpho Travassos; Edecio Cunha-Neto
Journal:  Mol Med       Date:  2003 Sep-Dec       Impact factor: 6.354

4.  Differential regulation of HLA-DR mRNAs and cell surface antigens by interferon.

Authors:  F Rosa; D Hatat; A Abadie; D Wallach; M Revel; M Fellous
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
  4 in total

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