Literature DB >> 6189923

Epidermal lipids, barrier function, and desquamation.

P M Elias.   

Abstract

Based on recent morphologic, histochemical, and biochemical data, we propose a heterogeneous two-compartment model of the stratum corneum that ascribes a special role for intercellular lipids in the regulation of stratum corneum barrier function and desquamation. The evidence in favor of the model and several predictions based on the model are surveyed in this review.

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Year:  1983        PMID: 6189923

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN: 0022-202X            Impact factor:   8.551


  90 in total

1.  Direct observation of domains in model stratum corneum lipid mixtures by Raman microspectroscopy.

Authors:  A Percot; M Lafleur
Journal:  Biophys J       Date:  2001-10       Impact factor: 4.033

2.  Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery.

Authors:  D Bommannan; H Okuyama; P Stauffer; R H Guy
Journal:  Pharm Res       Date:  1992-04       Impact factor: 4.200

3.  Overcoming the Barrier Treatment of Ichthyosis: A Combination-therapy Approach.

Authors:  Susun Bellew; James Q Del Rosso
Journal:  J Clin Aesthet Dermatol       Date:  2010-07

4.  Lipid composition of outer stratum corneum and nails in atopic and control subjects.

Authors:  B Melnik; J Hollmann; U Hofmann; M S Yuh; G Plewig
Journal:  Arch Dermatol Res       Date:  1990       Impact factor: 3.017

Review 5.  Epidermal barrier formation and recovery in skin disorders.

Authors:  Julia A Segre
Journal:  J Clin Invest       Date:  2006-05       Impact factor: 14.808

Review 6.  In vivo methods for the assessment of topical drug bioavailability.

Authors:  Christophe Herkenne; Ingo Alberti; Aarti Naik; Yogeshvar N Kalia; François-Xavier Mathy; Véronique Préat; Richard H Guy
Journal:  Pharm Res       Date:  2007-11-06       Impact factor: 4.200

7.  The effect of the proteolytic enzyme savinase on human plantar skin in vitro.

Authors:  S Imai
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017

Review 8.  Absorption of chemicals through compromised skin.

Authors:  Sanja Kezic; J B Nielsen
Journal:  Int Arch Occup Environ Health       Date:  2009-02-24       Impact factor: 3.015

9.  A microscopic multiphase diffusion model of viable epidermis permeability.

Authors:  Johannes M Nitsche; Gerald B Kasting
Journal:  Biophys J       Date:  2013-05-21       Impact factor: 4.033

10.  The influence of urea on percutaneous absorption.

Authors:  J Beastall; R H Guy; J Hadgraft; I Wilding
Journal:  Pharm Res       Date:  1986-10       Impact factor: 4.200

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