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Literature DB >> 6188725

Alcohol dehydrogenase in the mouse epididymis. Genetic variation and cellular localization.

Abstract

The cellular localization of alcohol dehydrogenase (ADH) in the mouse epididymis was investigated using differential substrate specificities and genetic variation as a means of distinguishing these enzymes histochemically in tissue sections. ADH-C2 exhibited high activity in BALB/c epididymis and was observed as a discrete zone within duct epithelial cells near the nuclei. This isozyme exhibited no detectable activity in C57BL/6J epididymis extracts or histochemical sections.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1983 PMID： 6188725 DOI： 10.1007/bf00496638

Source DB: PubMed Journal: Histochemistry ISSN： 0301-5564

5 in total

1. Histochemical studies on genetical control of hormonal enzyme inducibility in the mouse. I. Non-specific esterase activity and regional histology of the epididymis.

Authors: S R Blecher; S Kirkeby
Journal: J Anat Date: 1978-02 Impact factor: 2.610

2. Electrophoretic analyses of alcohol dehydrogenase, aldehyde dehydrogenase, aldehyde oxidase, sorbitol dehydrogenase and xanthine oxidase from mouse tissues.

Authors: R S Holmes
Journal: Comp Biochem Physiol B Date: 1978

3. Alcohol dehydrogenase isozymes in the mouse: genetic regulation, allelic variation among inbred strains and sex differences of liver and kidney A2 isozyme activity.

Authors: R S Holmes; J A Duley; S Imai
Journal: Anim Blood Groups Biochem Genet Date: 1982

4. Mouse alcohol dehydrogenase isozymes: products of closely localized duplicate genes exhibiting divergent kinetic properties.

Authors: R S Holmes; R Albanese; F D Whitehead; J A Duley
Journal: J Exp Zool Date: 1981-08

5. Genetics and ontogeny of alcohol dehydrogenase isozymes in the mouse: evidence for a cis-acting regulator gene (Adt-i) controlling C2 isozyme expression in reproductive tissues and close linkage of Adh-3 and Adt-i on chromosome 3.

Authors: R S Holmes
Journal: Biochem Genet Date: 1979-06 Impact factor: 1.890

5 in total

2 in total

1. Genetic considerations in the effects of ethanol in mice. II. A trans-acting inducibility regulator(s) affecting alcohol dehydrogenase (ADH) activity.

Authors: C H Wang; S M Singh
Journal: Biochem Genet Date: 1984-08 Impact factor: 1.890

2. Genetics of ocular NAD+-dependent alcohol dehydrogenase and aldehyde dehydrogenase in the mouse: evidence for genetic identity with stomach isozymes and localization of Ahd-4 on chromosome 11 near trembler.

Authors: R S Holmes; R A Popp; J L VandeBerg
Journal: Biochem Genet Date: 1988-04 Impact factor: 1.890

2 in total