Literature DB >> 6187613

Developmental regulation of myelin basic protein expression in mouse brain.

J H Carson, M L Nielson, E Barbarese.   

Abstract

Developmental regulation of myelin basic protein expression in mouse brain has been examined by comparing the myelin basic protein coding potential of mRNA in vitro with the accumulation of myelin basic protein-related polypeptides in vivo. In vitro translation of mRNA isolated from mouse brain generated eight myelin basic protein-related polypeptides with apparent molecular weights of 34K, 30K, 29K, 26K, 21.5K, 18.5K, 17K, and 14K. A similar set of eight myelin basic protein-related polypeptides with corresponding molecular weights was identified in vivo when total brain proteins were analyzed by immunoblotting. Each of the myelin basic protein-related polypeptides shows a characteristic developmental profile in terms of mRNA level and rate of accumulation implying a complex developmental program of myelin basic protein gene expression with regulation and modulation at several different biosynthetic levels.

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Year:  1983        PMID： 6187613     DOI： 10.1016/0012-1606(83)90185-9

Source DB:  PubMed          Journal:  Dev Biol        ISSN： 0012-1606            Impact factor:   3.582


  23 in total

1.  A transgenic mouse model for inducible and reversible dysmyelination.

Authors:  C Mathis; C Hindelang; M LeMeur; E Borrelli
Journal:  J Neurosci       Date:  2000-10-15       Impact factor: 6.167

Review 2.  Cellular and molecular aspects of myelin protein gene expression.

Authors:  A T Campagnoni; W B Macklin
Journal:  Mol Neurobiol       Date:  1988       Impact factor: 5.590

3.  Structure and expression of myelin basic protein gene sequences in the mld mutant mouse: reiteration and rearrangement of the MBP gene.

Authors:  A A Akowitz; E Barbarese; K Scheld; J H Carson
Journal:  Genetics       Date:  1987-07       Impact factor: 4.562

4.  Insertion of a retrotransposon in Mbp disrupts mRNA splicing and myelination in a new mutant rat.

Authors:  L T O'Connor; B D Goetz; J M Kwiecien; K H Delaney; A L Fletch; I D Duncan
Journal:  J Neurosci       Date:  1999-05-01       Impact factor: 6.167

5.  A mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin.

Authors:  Matthias Eckhardt; Afshin Yaghootfam; Simon N Fewou; Inge Zöller; Volkmar Gieselmann
Journal:  Biochem J       Date:  2005-05-15       Impact factor: 3.857

6.  Restoration of myelin formation by a single type of myelin basic protein in transgenic shiverer mice.

Authors:  M Kimura; M Sato; A Akatsuka; S Nozawa-Kimura; R Takahashi; M Yokoyama; T Nomura; M Katsuki
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

7.  The control of reactive oxygen species production by SHP-1 in oligodendrocytes.

Authors:  Ross C Gruber; Daria LaRocca; Scott B Minchenberg; George P Christophi; Chad A Hudson; Alex K Ray; Bridget Shafit-Zagardo; Paul T Massa
Journal:  Glia       Date:  2015-04-27       Impact factor: 7.452

8.  Magnetic resonance imaging and micro-computed tomography combined atlas of developing and adult mouse brains for stereotaxic surgery.

Authors:  M Aggarwal; J Zhang; M I Miller; R L Sidman; S Mori
Journal:  Neuroscience       Date:  2009-05-30       Impact factor: 3.590

9.  Analysis of the proximal transcriptional element of the myelin basic protein gene.

Authors:  K Devine-Beach; S Haas; K Khalili
Journal:  Nucleic Acids Res       Date:  1992-02-11       Impact factor: 16.971

10.  Myelin gene expression after experimental contusive spinal cord injury.

Authors:  J R Wrathall; W Li; L D Hudson
Journal:  J Neurosci       Date:  1998-11-01       Impact factor: 6.167
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