| Literature DB >> 6187380 |
H Petursson, P A Bond, B Smith, M H Lader.
Abstract
Long-term normal-dose benzodiazepine treatment in seven patients was associated with reduced urinary excretion of MOPEG (4-hydroxy-3-methoxy-phenylglycol). Following the discontinuation of the drugs a characteristic withdrawal reaction occurred, with an increase towards normal values of the MOPEG excretion levels and changes in the excretion of 5-HIAA (5-hydroxyindoleacetic acid). No significant changes in the 24-hr urinary excretion of free cortisol or HMMA (3-methoxy-hydroxy-mandelic acid) were detected.Entities:
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Year: 1983 PMID： 6187380
Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382