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Literature DB >> 6187169

T lymphocyte subpopulations in Graves' disease: relationship with clinical conditions.

M Bagnasco, G W Canonica, S Ferrini, P Biassoni, G Melioli, O Ferrini, G Giordano.

Abstract

T lymphocytes were fractionated according to their receptors for IgG (TG) or IgM (TM) and scored in 37 patients with Graves' disease (17 hyperthyroid and untreated. 10 euthyroid on antithyroid drugs, 10 in long-term remission after radioiodine therapy). TG percentages were very low both in untreated and in drug-treated patients. By contrast, normal TG levels were observed in patients in long-term remission. These data are consistent with the hypothesis of a defective suppressor cell activity in Graves' disease.

Entities: Chemical Disease Species

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Year: 1983 PMID： 6187169 DOI： 10.1530/acta.0.1020213

Source DB: PubMed Journal: Acta Endocrinol (Copenh) ISSN： 0001-5598

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Cited

7 in total

T lymphocyte subpopulations in Graves' disease: relationship with clinical conditions.

1. Studies on suppressor T lymphocyte function in Graves' disease by 3H-thymidine interpolation.

2. Immunological features of sporadic multinodular goiter.

3. Are antithyroid drugs immunosuppressive?

4. Incidence of T cell subset imbalance in relatives of Graves' disease patients.

5. Circulating T cell subsets in euthyroid Graves' disease.

6. Autoimmune thyroid disease: purification and phenotypic analysis of intrathyroid T cells.

7. T cell subsets and thyroid-stimulating antibodies in patients with Graves' disease in clinical remission.