Literature DB >> 6187067

Tunicamycin enhances the antiviral and anticellular activity of interferon.

R K Maheshwari, T Sreevalsan, R H Silverman, J Hay, R M Friedman.   

Abstract

The inhibitory effects of interferon on virus multiplication and cell growth are significantly enhanced by treatment with tunicamycin. Potentiation of antiviral activity was found only with enveloped viruses and not with nonbudding viruses. Changes in the plasma membrane of treated cells may account for this effect, since enveloped viruses bud from the cell surface as a terminal step.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6187067     DOI： 10.1126/science.6187067

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  2 in total

1.  Interferon-α alters host glycosylation machinery during treated HIV infection.

Authors:  Leila B Giron; Florent Colomb; Emmanouil Papasavvas; Livio Azzoni; Xiangfan Yin; Matthew Fair; Alitzel Anzurez; Mohammad Damra; Karam Mounzer; Jay R Kostman; Pablo Tebas; Una O'Doherty; Hiroaki Tateno; Qin Liu; Michael R Betts; Luis J Montaner; Mohamed Abdel-Mohsen
Journal:  EBioMedicine       Date:  2020-08-19       Impact factor: 8.143

2.  Tunicamycin treatment inhibits the antiviral activity of interferon in mice.

Authors:  R K Maheshwari; M M Husain; A M Attallah; R M Friedman
Journal:  Infect Immun       Date:  1983-07       Impact factor: 3.441
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.