Literature DB >> 6186369

Analysis of the role of membrane transport and polyglutamation of methotrexate in gut and the Ehrlich tumor in vivo as factors in drug sensitivity and selectivity.

D W Fry, L A Anderson, M Borst, I D Goldman.   

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Year:  1983        PMID: 6186369

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  24 in total

1.  The impact of 5-formyltetrahydrofolate on the anti-tumor activity of pralatrexate, as compared to methotrexate, in HeLa cells in vitro.

Authors:  Michele Visentin; Ersin Selcuk Unal; I David Goldman
Journal:  Cancer Chemother Pharmacol       Date:  2014-03-29       Impact factor: 3.333

2.  Alleviation by leucovorin of the dose-limiting toxicity of edatrexate: potential for improved therapeutic efficacy.

Authors:  J S Lee; W K Murphy; M H Shirinian; A Pang; W K Hong
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

Review 3.  Polyglutamation of methotrexate. Is methotrexate a prodrug?

Authors:  B A Chabner; C J Allegra; G A Curt; N J Clendeninn; J Baram; S Koizumi; J C Drake; J Jolivet
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

4.  Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.

Authors:  S Koizumi; G A Curt; R L Fine; J D Griffin; B A Chabner
Journal:  J Clin Invest       Date:  1985-03       Impact factor: 14.808

5.  Kinetic simulation of anticancer drug effects on metabolic pathway fluxes: two case studies.

Authors:  R C Jackson
Journal:  Bull Math Biol       Date:  1986       Impact factor: 1.758

Review 6.  Pharmacokinetics of anticancer drugs in children.

Authors:  W R Crom; A M Glynn-Barnhart; J H Rodman; M E Teresi; R E Kavanagh; M L Christensen; M V Relling; W E Evans
Journal:  Clin Pharmacokinet       Date:  1987-03       Impact factor: 6.447

7.  Anticytomegaloviral activity of methotrexate associated with preferential accumulation of drug by cytomegalovirus-infected cells.

Authors:  M Wachsman; F M Hamzeh; H Saito; P S Lietman
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

8.  Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells.

Authors:  R L Schilsky; F S Ordway
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

9.  Differential calcium leucovorin protection of human lymphoid cell lines from methotrexate.

Authors:  G P Browman; L Booker; P Spiegl
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

10.  Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow.

Authors:  J Baram; C J Allegra; R L Fine; B A Chabner
Journal:  J Clin Invest       Date:  1987-03       Impact factor: 14.808

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