Literature DB >> 6185435

Additive effects of acyclovir and immune transfer in neonatal herpes simplex virus infection in mice.

S Kohl.   

Abstract

Acyclovir had a dose-dependent, mild, but significant, inhibitory effect on interferon-stimulated human antiviral natural killer cytotoxicity in vitro. In a murine model of neonatal herpes simplex virus infection, acyclovir significantly (P < 0.05) increased survival afforded by the injection of human interferon and human mononuclear leukocytes from 67.8 to 88.6%.

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Year:  1983        PMID: 6185435      PMCID: PMC347969          DOI: 10.1128/iai.39.1.480-482.1983

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  6 in total

1.  Interferon induction of natural killer cytotoxicity in human neonates.

Authors:  S Kohl; J J Frazier; S B Greenberg; L K Pickering; L S Loo
Journal:  J Pediatr       Date:  1981-03       Impact factor: 4.406

2.  Protection of newborn mice from a lethal herpes simplex virus infection by human interferon, antibody, and leukocytes.

Authors:  S Kohl; L S Loo; S B Greenberg
Journal:  J Immunol       Date:  1982-03       Impact factor: 5.422

Review 3.  Drug therapy: antiviral agents (second of two parts).

Authors:  M S Hirsch; M N Swartz
Journal:  N Engl J Med       Date:  1980-04-24       Impact factor: 91.245

4.  Vidarabine therapy of neonatal herpes simplex virus infection.

Authors:  R J Whitley; A J Nahmias; S J Soong; G G Galasso; C L Fleming; C A Alford
Journal:  Pediatrics       Date:  1980-10       Impact factor: 7.124

Review 5.  Natural killer cells: their roles in defenses against disease.

Authors:  R B Herberman; J R Ortaldo
Journal:  Science       Date:  1981-10-02       Impact factor: 47.728

6.  Ontogeny of murine cellular cytotoxicity to herpes simplex virus-infected cells.

Authors:  S Kohl; L S Loo
Journal:  Infect Immun       Date:  1980-12       Impact factor: 3.441

  6 in total
  2 in total

1.  Protective T-cell-based immunity induced in neonatal mice by a single replicative cycle of herpes simplex virus.

Authors:  M Franchini; C Abril; C Schwerdel; C Ruedl; M Ackermann; M Suter
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

2.  The Innate Immune Response to Herpes Simplex Virus 1 Infection Is Dampened in the Newborn Brain and Can Be Modulated by Exogenous Interferon Beta To Improve Survival.

Authors:  Daniel Giraldo; Douglas R Wilcox; Richard Longnecker
Journal:  mBio       Date:  2020-05-26       Impact factor: 7.867

  2 in total

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