| Literature DB >> 6185435 |
Abstract
Acyclovir had a dose-dependent, mild, but significant, inhibitory effect on interferon-stimulated human antiviral natural killer cytotoxicity in vitro. In a murine model of neonatal herpes simplex virus infection, acyclovir significantly (P < 0.05) increased survival afforded by the injection of human interferon and human mononuclear leukocytes from 67.8 to 88.6%.Entities:
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Year: 1983 PMID: 6185435 PMCID: PMC347969 DOI: 10.1128/iai.39.1.480-482.1983
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441