Literature DB >> 6184417

Mouse monoclonal anti-N. I. Production and serological characterization.

R H Fraser, A C Munro, A R Williamson, E K Barrie, E A Hamilton, R Mitchell.   

Abstract

Two examples of mouse monoclonal anti-N are described. The antibodies were derived from mice immunized with sialoglycoprotein extracts of group O MM ss erythrocyte membranes and the probable stimulus for immunization was glycophorin B associated N-antigen. Both antibodies reacted as direct agglutinins but appeared to recognize different epitopes with one having a greater dependence on sialic acid. The antibodies could prove to be valuable alternatives to those reagents used currently for N-blood grouping.

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Year:  1982        PMID: 6184417     DOI: 10.1111/j.1744-313x.1982.tb00985.x

Source DB:  PubMed          Journal:  J Immunogenet        ISSN: 0305-1811


  1 in total

1.  The quantification of erythrocyte antigen sites with monoclonal antibodies.

Authors:  A H Merry; E E Thomson; D J Anstee; F Stratton
Journal:  Immunology       Date:  1984-04       Impact factor: 7.397

  1 in total

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