Literature DB >> 6184252

The crypto-OH radical in the damage of DNA by bleomycin-Fe2+?

A Bartkowiak, E Grzelinska, G Bartosz, J Zabłocka, W Leyko.   

Abstract

1. Effects of various OH scavengers, superoxide dismutase and catalase on the formation of malondialdehyde-like products from DNA by bleomycin-Fe2+ were studied. In no case was a protective effect observed. 2. These results can be interpreted on the basis that a crypto-OH radical mediates the damage to DNA by bleomycin-Fe2+.

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Year:  1982        PMID: 6184252     DOI: 10.1016/0020-711x(82)90160-4

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  2 in total

1.  ESR of copper and iron complexes with antitumor and cytotoxic properties.

Authors:  W E Antholine; B Kalyanaraman; D H Petering
Journal:  Environ Health Perspect       Date:  1985-12       Impact factor: 9.031

2.  Polyoxyethylene-modified superoxide dismutase reduces side effects of adriamycin and mitomycin C.

Authors:  S Kawasaki; S Akiyama; T Kurokawa; M Kataoka; K Dohmitsu; K Kondoh; M Yamauchi; K Ito; T Watanabe; S Sugiyama
Journal:  Jpn J Cancer Res       Date:  1992-08
  2 in total

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