Literature DB >> 6183087

[Raynaud's phenomenon following combined cytostatic treatment of malignant testicular tumours].

M E Scheulen, C G Schmidt.   

Abstract

Raynaud's phenomenon was observed in 8 out of 271 patients with malignant testicular tumours during or up to 14 months after combined cytostatic treatment. All patients with Raynaud's phenomenon were part of a group of 30 people having received vinblastine in a total dose of at least 2 mg/kg and bleomycin in a dose of 10 mg/kg. There were no other hints of Raynaud's syndrome from the history or chemical pathology. Compared to the experience of other authors Raynaud's phenomenon was observed less frequently and only at dosages of vinblastine and bleomycin considerably higher. This may possibly be due to use of steroids during combined cytostatic treatment with vinblastine and bleomycin.

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Year:  1982        PMID: 6183087     DOI: 10.1055/s-2008-1070180

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  1 in total

Review 1.  Drug-induced Raynaud's phenomenon: beyond β-adrenoceptor blockers.

Authors:  Charles Khouri; Sophie Blaise; Patrick Carpentier; Céline Villier; Jean-Luc Cracowski; Matthieu Roustit
Journal:  Br J Clin Pharmacol       Date:  2016-04-07       Impact factor: 4.335

  1 in total

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