Observations on the Anton antigen and antibody.

Five antisera with Anton specificity were studied serologically. The determinant is not sensitive to treatment by proteolytic enzymes (notably trypsin) and is present on cells of the recessive type of Lu(a-b-) phenotype. The Anton 'para-Lutheran' antigen/antibody therefore seems to be associated with the Lutheran blood group system only by means of cells of the dominant type of the Lu(a-b-) phenotype which is controlled by In(Lu), a gene independent of the Lutheran locus.