Bioadhesives in cardiac and vascular surgery.

Bleeding through the pores of thoracic vascular grafts sealed with bioadhesive has been eliminated without inducing additional defects in the coagulation system. This has been true regardless of whether additional valve replacement or aorto-coronary bypass procedures were performed. The operative risk and the need for blood transfusions has been lowered significantly thus reducing the cost of these procedures. Bioadhesive has been also applied successfully in a variety of perioperative bleeding complications.