Literature DB >> 6182041

Characterization, origin and evolution of alpha-fetoprotein and albumin in postnatal rat brain.

A Piñeiro, M Calvo, F Iguaz, F Lampreave, J Naval.   

Abstract

1. The levels of AFP and albumin in rat brain at birth were 77 and 340 micrograms per g of tissue, respectively. These levels quickly dropped with age. AFP was undetectable in 20 days brain extracts whereas 30 micrograms of albumin per g of brain were still measured. 2. AFP from brain and serum were identical by immunodiffusion, electrophoresis and immuno-affinoelectrophoresis with free Concanavalin A. 3. No in vitro synthesis of AFP and albumin in the postnatal brain was observed. However, the total amount of AFP in the developing rat brain increases from birth to 4-5 days post-partum.

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Year:  1982        PMID: 6182041     DOI: 10.1016/0020-711x(82)90103-3

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  6 in total

1.  Alpha-fetoprotein (AFP) in granulomatous inflammation of the mouse.

Authors:  J Trojan; J Naval; H Jusforgues; J Uriel
Journal:  Br J Exp Pathol       Date:  1989-08

2.  Cell-type-specific receptors for alpha-fetoprotein in a mouse T-lymphoma cell line.

Authors:  J Naval; M J Villacampa; A F Goguel; J Uriel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

3.  Developmental time course of estradiol, testosterone, and dihydrotestosterone levels in discrete regions of male and female rat brain.

Authors:  Anne T M Konkle; Margaret M McCarthy
Journal:  Endocrinology       Date:  2010-11-10       Impact factor: 4.736

4.  The distribution of native albumin and foreign albumin injected into lateral ventricles of prenatal and neonatal rat forebrains.

Authors:  M E Cavanagh; A Warren
Journal:  Anat Embryol (Berl)       Date:  1985

5.  Fetuin as a marker of cortical plate cells in the fetal cow neocortex: a comparison of the distribution of fetuin, alpha 2HS-glycoprotein, alpha-fetoprotein and albumin during early development.

Authors:  M L Reynolds; M E Sarantis; F L Lorscheider; N R Saunders
Journal:  Anat Embryol (Berl)       Date:  1987

6.  The uptake of alpha-foetoprotein by C-1300 mouse neuroblastoma cells.

Authors:  M Hajeri-Germond; J Naval; J Trojan; J Uriel
Journal:  Br J Cancer       Date:  1985-06       Impact factor: 7.640

  6 in total

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