Literature DB >> 6181038

A monoclonal antibody against an epitope common to HLA-b locus antigens.

R Billing, K Lucero.   

Abstract

A monoclonal antibody G4 that appears to be directed against a determinant common to all HLA-B locus antigens is described. This antibody reacted with a large panel of B and T lymphocyte and cell lines, but it did not react with two lines that do not serologically express HLA antigens (Daudi and K562) and two lines that expressed A-locus but not B-locus antigens (8402 and HPBMLT). The F(ab')2 fragment of G4 blocked B-locus but not A-locus HLA alloantisera. By immunoprecipitation and SDS-polyacrylamide gel electrophoresis G4 reacted with a dimer consisting of a heavy chain of 44,000 daltons and a light chain of 12,7000 daltons.

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Year:  1982        PMID： 6181038     DOI： 10.1016/0198-8859(82)90008-8

Source DB:  PubMed          Journal:  Hum Immunol        ISSN： 0198-8859            Impact factor:   2.850


  8 in total

1.  Expression of an HLA-Bw6-related specificity by the HLA-Cw3 molecule.

Authors:  C Layet; T Delovitch; P Ferrier; D H Caillol; B R Jordan; F A Lemonnier
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

2.  Transfection of murine LMTK- cells with purified HLA class I genes. VII. Association of allele- and locus-specific serological reactivities with respectively the first and second domains of the HLA-B7 molecule.

Authors:  R Sodoyer; B Kahn-Perles; T Strachan; J Sire; M J Santoni; C Layet; P Ferrier; B R Jordan; F A Lemonnier
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

3.  Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids.

Authors:  R D Salter; D N Howell; P Cresswell
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

Review 4.  Comparison of the primary structure of class I molecules.

Authors:  W L Maloy
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

5.  A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.

Authors:  F M Brodsky
Journal:  Immunogenetics       Date:  1984       Impact factor: 2.846

6.  Transformation of LMTK- cells with purified HLA class I genes. II. Serologic characterization of HLA-A3 and CW3 molecules.

Authors:  F A Lemonnier; P C Dubreuil; C Layet; M Malissen; D Bourel; P Mercier; B K Jakobsen; D H Caillol; A Svejgaard; F M Kourilsky; B R Jordan
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

7.  Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid.

Authors:  R D Salter; P Cresswell
Journal:  EMBO J       Date:  1986-05       Impact factor: 11.598

8.  Evidence for a shared HLA-A intralocus determinant defined by monoclonal antibody 131.

Authors:  B T Spear; J Kornbluth; J L Strominger; D B Wilson
Journal:  J Exp Med       Date:  1985-12-01       Impact factor: 14.307
  8 in total

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