| Literature DB >> 6180972 |
C J Secombes, M J Manning, A E Ellis.
Abstract
In carp Cyprinus carpio L. preimmunized with a protein antigen, human gamma globulin (HGG), rapid localization of antigen occurred in the splenic ellipsoids within 1 day of a secondary immunization given 8 weeks later. Furthermore, after injection of immune complexes or heat-aggregated HGG, antigen was trapped more quickly in the pronephros than when antigen was injected alone. These results support the conclusion that in fish, as in homoiotherms, this form of antigen trapping is antibody-dependent.Entities:
Mesh：
Substances：
Year: 1982 PMID： 6180972 PMCID： PMC1555507
Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397