Literature DB >> 6179486

Effect of cannabinoids on the activity of monoamine oxidase in normal human platelets.

M Mazor, A Dvilansky, M Aharon, Z Lazarovitz, I Nathan.   

Abstract

Platelet MAO activity was affected by preincubation with cannabinoid derivatives in vitro. The psycho-active derivative delta 1-THC inhibited MAO activity in platelets to an extent varying according to its concentration while CBD and (+) delta 6-THC had no inhibitory effect. (-) delta 6-THC, which is minor psychomimetic component, had less inhibitory effect on MAO activity than delta 1-THC. However, (-) DMH delta 6-THC revealed no attenuation effect on MAO inspite of its well-known psychomimetic activity.

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Year:  1982        PMID: 6179486     DOI: 10.3109/13813458209082649

Source DB:  PubMed          Journal:  Arch Int Physiol Biochim        ISSN: 0003-9799


  3 in total

1.  Interactions of endocannabinoid virodhamine and related analogs with human monoamine oxidase-A and -B.

Authors:  Pankaj Pandey; Narayan D Chaurasiya; Babu L Tekwani; Robert J Doerksen
Journal:  Biochem Pharmacol       Date:  2018-06-26       Impact factor: 5.858

2.  Inhibition of monoamine oxidase activity by cannabinoids.

Authors:  Zdenek Fisar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2010-04-18       Impact factor: 3.000

Review 3.  Regulatory Effects of Cannabidiol on Mitochondrial Functions: A Review.

Authors:  John Zewen Chan; Robin Elaine Duncan
Journal:  Cells       Date:  2021-05-19       Impact factor: 6.600

  3 in total

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