Histochemical studies on striated muscle fibres of the beige mutant mouse.

A histological study of cylindric structures in skeletal muscle fibres from beige mice with the Chediak-Higashi syndrome was carried out. The muscle tissue was investigated morphologically with a differential interference contrast microscope and stained for glycogen, lipid, and basophile elements. It is suggested that the cylindric structures represent accumulations of glycogen rich lipoprotein membranes.