| Literature DB >> 6178839 |
M W Cloyd, B Chesebro, J L Portis, M Weir.
Abstract
Hybridomas obtained from (NFS X AKR)F mice immunized with syngeneic cells infected with AKR-247 MCF virus produced antibodies specific for only AKR-247 or closely related MCF viruses which hare a previously defined MCF antigen (MCFA-3). These monoclonal antibodies recognized a new type of viral antigenic determinant which appeared to be a conformational determinant associated with the env precursor polyprotein (pr80env) or its disulfide-linked gp70-p15(E) complex (gp80) but not with free gp70 or p15(E) or any other virion or virus-induced protein.Entities:
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Year: 1982 PMID: 6178839 PMCID: PMC256853 DOI: 10.1128/JVI.41.3.1112-1117.1982
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103