Literature DB >> 6178616

Effect of des-Tyr1-gamma-endorphin on serotonin metabolism in rat brain regions.

M Kurachi, D H Versteeg, J M Van Ree, H G Westernberg, H M Van Praag.   

Abstract

Intracerebroventricular (i.c.v.) administration of des-Tyr1-gamma-endorphin (0.1 and 1.0 microgram) caused a decrease of the serotonin (5-HT) concentration of the hippocampus. The concentration of 5-HIAA and the pargyline-induced alterations in 5-HT and 5-HIAA were not affected. No effects were noticed in other brain regions.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6178616     DOI： 10.1007/BF02327070

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Neuroleptic activity of the neuropeptide beta-LPH62-77 ([Des-Tyr1]gamma-endorphin; DT gamma E).

Authors:  D De Wied; G L Kovács; B Bohus; J M Van Ree; H M Greven
Journal:  Eur J Pharmacol       Date:  1978-06-15       Impact factor: 4.432

2.  Opiate-receptor mediated changes in monoamine synthesis in rat brain.

Authors:  J A Garcia-Sevilla; L Ahtee; T Magnusson; A Carlsson
Journal:  J Pharm Pharmacol       Date:  1978-10       Impact factor: 3.765

Review 3.  Roles of serotonin and gamma-aminobutyric acid in opioid effects.

Authors:  D A Brase
Journal:  Adv Biochem Psychopharmacol       Date:  1979

4.  Brain RNA and hypophysectomy; a topographical study.

Authors:  W H Gispen; P Schotman; E R de Kloet
Journal:  Neuroendocrinology       Date:  1972       Impact factor: 4.914

5.  Serotonergic component of neuroleptic receptors.

Authors:  J E Leysen; C J Niemegeers; J P Tollenaere; P M Laduron
Journal:  Nature       Date:  1978-03-09       Impact factor: 49.962

6.  Examination of des-tyrosine1-gamma-endorphin activity at oH-spiroperidol binding sites in rat brain.

Authors:  N W Pedigo; N C Ling; T D Reisine; H I Yamamura
Journal:  Life Sci       Date:  1979-04-30       Impact factor: 5.037

7.  Effects of alpha-endorphin, beta-endorphin and (des-tyr1)-gamma-endorphin on alpha-MPT-induced cateholamine disappearance in discrete regions of the rat brain.

Authors:  D H Versteeg; E R De Kloet; D De Wied
Journal:  Brain Res       Date:  1979-12-21       Impact factor: 3.252

8.  Interaction of des-tyrosine-gamma-endorphin (DTgammaE, beta-LPH62-77) with neuroleptic binding sites in various areas of rat brain.

Authors:  J M van Ree; A Witter; J E Leysen
Journal:  Eur J Pharmacol       Date:  1978-12-01       Impact factor: 4.432

9.  Improvement of schizophrenic patients treated with [des-Tyr1]-gamma-endorphin (DTgammaE).

Authors:  W M Verhoeven; H M van Praag; J M van Ree; D de Wied
Journal:  Arch Gen Psychiatry       Date:  1979-03

10.  Inhibition of in vivo 3H-spiperone binding by the proposed antipsychotic Des-Tyr1-gamma-endorphin.

Authors:  N W Pedigo; T Schallert; D H Overstreet; N C Ling; P Ragan; T D Reisine; H I Yamamura
Journal:  Eur J Pharmacol       Date:  1979-12-20       Impact factor: 4.432
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.