Literature DB >> 6178588

Subacute sclerosing panencephalitis in a brother and sister. Therapeutic trial of fibroblast interferon.

C R Bartram, J Henke, J Treuner, M Basler, A Esch, W Mortier.   

Abstract

This paper describes the very rare occurrence of subacute sclerosing panencephalitis (SSPE) in two siblings: a Turkish boy and his younger sister. The clinical picture was characteristic, and the diagnosis was confirmed in both cases by appropriate laboratory examination. The interval between the occurrence of the first neurological symptoms in the boy, and subsequently in the girl was four years. Study of HLA- and 27 other polymorphic marker-systems did not reveal linkage to one of the systems tested. Therapeutic trials in the girl included intravenous and intraventricular application of a total of 87 X 10(6) U human fibroblast interferon (Hu INF-beta) over 21 days. However, up to 3 months after the end of interferon administration there were no significant changes in the girl's condition.

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Year:  1982        PMID： 6178588     DOI： 10.1007/BF00441152

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  16 in total

1.  Subacute sclerosing panencephalitis in only one member of a monozygotic twin pair. Clinical, laboratory, electroencephalographic, and immunological study of both twins.

Authors:  A D'Onghia; A B Lefévre; H M Canelas; R M Grossmann; L F Salles-Gomes; P H Saldanha
Journal:  J Neurol Sci       Date:  1974-03       Impact factor: 3.181

2.  Successful treatment of nasopharyngeal carcinoma with interferon.

Authors:  J Treuner; D Niethammer; G Dannecker; R Hagmann; V Neef; P H Hofschneider
Journal:  Lancet       Date:  1980-04-12       Impact factor: 79.321

Review 3.  Interferon therapy: pharmacokinetic and pharmacological aspects.

Authors:  A Billiau
Journal:  Arch Virol       Date:  1981       Impact factor: 2.574

4.  Interferon in treatment of subacute sclerosing panencephalitis.

Authors:  P O Behan
Journal:  Lancet       Date:  1981-05-09       Impact factor: 79.321

5.  Letter: HL-A W29 and subacute sclerosing panencephalitis.

Authors:  J E Kurent; J L Sever; P I Terasaki
Journal:  Lancet       Date:  1975-04-19       Impact factor: 79.321

6.  Subacute sclerosing panencephalitis in only one of identical twins. A seven-year follow-up.

Authors:  S A Houff; D L Madden; J L Sever
Journal:  Arch Neurol       Date:  1979-12

7.  Substantial spontaneous long-term improvement in subacute sclerosing panencephalitis. Six cases from the Middle East and a review of the literature.

Authors:  W S Risk; F S Haddad; R Chemali
Journal:  Arch Neurol       Date:  1978-08

8.  Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis.

Authors:  W W Hall; R A Lamb; P W Choppin
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

9.  Review of 38 cases of subacute sclerosing panencephalitis: effect of amantadine on the natural course of the disease.

Authors:  W C Robertson; D B Clark; W R Markesbery
Journal:  Ann Neurol       Date:  1980-10       Impact factor: 10.422

10.  Isoprinosine treatment in 18 patients with subacute sclerosing panencephalitis: a controlled study.

Authors:  F S Haddad; W S Risk
Journal:  Ann Neurol       Date:  1980-02       Impact factor: 10.422
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  2 in total

1.  Increase of predominantly k-type light chains in the CSF of a case of subacute sclerosing panencephalitis treated with interferon.

Authors:  P Annunziata; A Battista; G C Guazzi
Journal:  Ital J Neurol Sci       Date:  1985-06

2.  Identification of a nonproductive, cell-associated form of measles virus by its resistance to inhibition by recombinant human interferon.

Authors:  D R Carrigan; C M Kabacoff
Journal:  J Virol       Date:  1987-06       Impact factor: 5.103
  2 in total

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