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Literature DB >> 6177865

Production and characterization of monoclonal antibodies against the Epstein-Barr virus membrane antigen.

B C Strnad, T Schuster, R Klein, R F Hopkins, T Witmer, R H Neubauer, H Rabin.

Abstract

Five murine hybridoma lines that produce monoclonal antibodies against Epstein-Barr virus membrane antigen (MA) were established. Immunoprecipitation experiments demonstrated that three of the antibodies precipitated both the 236,000 (236K) MA and the 212K MA. The other two antibodies precipitated the 86K MA. Antibodies against the 236K-212K MA and the 86K MA mediated complement-dependent cytolysis of Epstein-Barr-virus-infected cells. The antibodies against the 86K MA neutralized both the B95-8 and P3HR-1 viruses.

Entities: Disease Species

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Year: 1982 PMID： 6177865 PMCID： PMC256747 DOI： 10.1128/JVI.41.1.258-264.1982

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

16 in total

1. Analysis of early and late Epstein-Barr virus associated polypeptides by immunoprecipitation.

Authors: N Mueller-Lantzsch; N Yamamoto; H zur Hausen
Journal: Virology Date: 1979-09 Impact factor: 3.616

2. The isolation of hybrid cell lines producing monoclonal antibodies against the p15(E) protein of ecotropic murine leukemia viruses.

Authors: R C Nowinski; M E Lostrom; M R Tam; M R Stone; W N Burnette
Journal: Virology Date: 1979-02 Impact factor: 3.616

3. Persisting oncogenic herpesvirus induced by the tumour promotor TPA.

Authors: H zur Hausen; F J O'Neill; U K Freese; E Hecker
Journal: Nature Date: 1978-03-23 Impact factor: 49.962

4. Biochemical identification of primate lymphoid cell-surface glycoproteins.

Authors: B C Strnad; R H Neubauer; H Rabin
Journal: Int J Cancer Date: 1979-01-15 Impact factor: 7.396

5. Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3alpha,6alpha-diphenylglycoluril.

Authors: M A Markwell; C F Fox
Journal: Biochemistry Date: 1978-10-31 Impact factor: 3.162

6. External labeling of cell surface galactose and galactosamine in glycolipid and glycoprotein of human erythrocytes.

Authors: C G Gahmberg; S I Hakomori
Journal: J Biol Chem Date: 1973-06-25 Impact factor: 5.157

7. Different surface glycoprotein patterns on human T-, B- and leukemic-lymphocytes.

Authors: L C Andersson; C Wasastjerna; C G Gahmberg
Journal: Int J Cancer Date: 1976-01-15 Impact factor: 7.396

8. Polypeptides of the Epstein-Barr virus membrane antigen complex.

Authors: D A Thorley-Lawson; C M Edson
Journal: J Virol Date: 1979-11 Impact factor: 5.103

9. Epstein-Barr virus-induced membrane antigens: immunochemical characterization of Triton X-100 solubilized viral membrane antigens from EBV-superinfected Raji cells.

Authors: L F Qualtiere; G R Pearson
Journal: Int J Cancer Date: 1979-06-15 Impact factor: 7.396

10. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.

Authors: P J Fraker; J C Speck
Journal: Biochem Biophys Res Commun Date: 1978-02-28 Impact factor: 3.575

52 in total

1. Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion.

Authors: Austin N Kirschner; Jasmina Omerovic; Boris Popov; Richard Longnecker; Theodore S Jardetzky
Journal: J Virol Date: 2006-10 Impact factor: 5.103

2. Cell-surface expression of a mutated Epstein-Barr virus glycoprotein B allows fusion independent of other viral proteins.

Authors: Marisa P McShane; Richard Longnecker
Journal: Proc Natl Acad Sci U S A Date: 2004-12-06 Impact factor: 11.205

Review 3. Epstein-Barr virus tissue tropism: a major determinant of immunopathogenesis.

Authors: L Hutt-Fletcher
Journal: Springer Semin Immunopathol Date: 1991

4. Pseudorabies virus glycoprotein L is necessary for virus infectivity but dispensable for virion localization of glycoprotein H.

Authors: B G Klupp; W Fuchs; E Weiland; T C Mettenleiter
Journal: J Virol Date: 1997-10 Impact factor: 5.103

Review 5. Epstein-Barr virus entry.

Authors: Lindsey M Hutt-Fletcher
Journal: J Virol Date: 2007-04-25 Impact factor: 5.103

6. Binding-site interactions between Epstein-Barr virus fusion proteins gp42 and gH/gL reveal a peptide that inhibits both epithelial and B-cell membrane fusion.

Authors: Austin N Kirschner; Amanda S Lowrey; Richard Longnecker; Theodore S Jardetzky
Journal: J Virol Date: 2007-06-20 Impact factor: 5.103

7. Depletion of glycoprotein gp85 from virosomes made with Epstein-Barr virus proteins abolishes their ability to fuse with virus receptor-bearing cells.

Authors: R S Haddad; L M Hutt-Fletcher
Journal: J Virol Date: 1989-12 Impact factor: 5.103