Literature DB >> 6177816

Direct demonstration of an HLA-DR allotypic determinant on the low molecular weight (beta) subunit using a mouse monoclonal antibody specific for DR3.

J P Johnson, T Meo, G Riethmüller, D J Schendel, R Wank.   

Abstract

A murine monoclonal antibody directed against a human B cell surface antigen with the characteristics of HLA-DR is described. The antigen detected is tightly linked to HLA and is correlated with the alloantigen HLA-Dw/DR3. Reactivity with a fraction of Dw/DRw6 cells is also observed. The determinant recognized by this antibody has been shown to be present on the smaller molecular weight beta subunit of the HLA-DR antigen.

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Year:  1982        PMID： 6177816      PMCID： PMC2186719          DOI： 10.1084/jem.156.1.104

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  19 in total

Review 1.  Murine monoclonal antibodies against HLA structures.

Authors:  M M Trucco; G Garotta; J W Stocker; R Ceppellini
Journal:  Immunol Rev       Date:  1979       Impact factor: 12.988

2.  Polymorphism of human B-cell alloantigens: evidence for three loci within the HLA system.

Authors:  M L Markert; P Cresswell
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

3.  Heavy HLA-DR (Ia) antigen chain is controlled by the MHC region.

Authors:  L Klareskog; L Rask; J Fohlman; P A Peterson
Journal:  Nature       Date:  1978-10-26       Impact factor: 49.962

4.  Subsets of human Ia-like molecules defined by monoclonal antibodies.

Authors:  S Carrel; R Tosi; N Gross; N Tanigaki; A L Carmagnola; R S Accolla
Journal:  Mol Immunol       Date:  1981-05       Impact factor: 4.407

5.  Two populations of Ia-like molecules on a human B cell line.

Authors:  L A Lampson; R Levy
Journal:  J Immunol       Date:  1980-07       Impact factor: 5.422

6.  Characterization of HLA-D-region antigens by two-dimensional gel electrophoresis. Molecular-genotyping.

Authors:  D J Charron; H O McDevitt
Journal:  J Exp Med       Date:  1980-08-01       Impact factor: 14.307

7.  Assays for cellular antigens in the presence of detergents.

Authors:  A F Williams
Journal:  Eur J Immunol       Date:  1973-10       Impact factor: 5.532

8.  Structural polymorphism of human DR antigens.

Authors:  J Silver; S Ferrone
Journal:  Nature       Date:  1979-05-31       Impact factor: 49.962

9.  HLA-D restriction of the macrophage-dependent response of immune human T lymphocytes to PPD in vitro: inhibition by anti-HLA-DR antisera.

Authors:  B O Bergholtz; E Thorsby
Journal:  Scand J Immunol       Date:  1978       Impact factor: 3.487

10.  Surface antigens of human melanoma cells defined by monoclonal antibodies. I. Biochemical characterization of two antigens found on cell lines and fresh tumors of diverse tissue origin.

Authors:  J P Johnson; M Demmer-Dieckmann; T Meo; M R Hadam; G Riethmüller
Journal:  Eur J Immunol       Date:  1981-10       Impact factor: 5.532
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  25 in total

1.  Point mutations define positions in HLA-DR3 molecules that affect antigen presentation.

Authors:  E Mellins; B Arp; D Singh; B Carreno; L Smith; A H Johnson; D Pious
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

2.  Analysis of HLA-DMB mutants and -DMB genomic structure.

Authors:  J Shaman; E von Scheven; P Morris; M D Chang; E Mellins
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

3.  Multiple signals regulate the intracellular trafficking of HLA-DM in B-lymphoblastoid cells.

Authors:  J Copier; P Potter; S H Sacks; A P Kelly
Journal:  Immunology       Date:  1998-04       Impact factor: 7.397

4.  In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM.

Authors:  L Lightstone; R Hargreaves; G Bobek; M Peterson; G Aichinger; G Lombardi; R Lechler
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-27       Impact factor: 11.205

5.  Differential expression of Ia antigens by rheumatoid synovial lining cells.

Authors:  G R Burmester; B Jahn; P Rohwer; J Zacher; R J Winchester; J R Kalden
Journal:  J Clin Invest       Date:  1987-09       Impact factor: 14.808

6.  A pathogenetic role for the thymoma in myasthenia gravis. Autosensitization of IL-4- producing T cell clones recognizing extracellular acetylcholine receptor epitopes presented by minority class II isotypes.

Authors:  N Nagvekar; A M Moody; P Moss; I Roxanis; J Curnow; D Beeson; N Pantic; J Newsom-Davis; A Vincent; N Willcox
Journal:  J Clin Invest       Date:  1998-05-15       Impact factor: 14.808

7.  Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids.

Authors:  R D Salter; D N Howell; P Cresswell
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

8.  Molecular genotyping of the HLA-DQ alpha gene region.

Authors:  J Guardiola; A Maffei; S Carrel; R S Accolla
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

9.  Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome.

Authors:  S Kovats; G T Nepom; M Coleman; B Nepom; W W Kwok; J S Blum
Journal:  J Clin Invest       Date:  1995-07       Impact factor: 14.808

10.  Inhibition of autologous mixed lymphocyte reaction by monoclonal antibodies specific for the beta chain of HLA-DR antigens.

Authors:  M Kasahara; H Ikeda; K Ogasawara; N Ishikawa; T Okuyama; Y Fukasawa; H Kojima; H Kunikane; S Hawkin; T Ohhashi
Journal:  Immunology       Date:  1984-09       Impact factor: 7.397
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